Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213632 | 0.85 | KIF11 (0.46) | TDP1ERN1KDM4EHSD17B10MAPT | |
| SCHEMBL16579516 | 0.85 | TDP1 (0.52) | TDP1ERN1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL868931 | 0.84 | ERN1 (0.52) | TDP1ERN1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL28240259 | 0.82 | TDP1 (0.40) | TDP1ERN1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL15823461 | 0.81 | AR (0.56) | TDP1ERN1KDM4ESMN1; SMN2 | |
| SCHEMBL9996385 | 0.80 | HCAR1 (0.39) | TDP1RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9996387 | 0.80 | HCAR1 (0.39) | TDP1RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL472401 | 0.78 | CES2 (0.50) | ERN1HCAR1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6852469 | 0.78 | APP (0.49) | TDP1ERN1RAB9AKDM4EHSD17B10 | |
| SCHEMBL333114 | 0.78 | IDO1 (0.42) | ERN1HCAR1KDM4EPTPN1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48335-E1 | Polymyxin derivatives as antimicrobial compounds | MONASH UNIVERSITY (AU) | 2020-12-01 | — | — | US | claimed |
| CN-108529988-B | Impervious concrete for shield segment and preparation method thereof | 北京港创瑞博混凝土有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-106414480-B | Polymyxin derivatives as antimicrobial compounds | 莫纳什大学 | 2020-08-04 | — | — | CN | claimed |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2017-05-18 | — | — | US | claimed |
| EP-3126376-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | Monash University (AU) | 2017-02-08 | — | — | EP | claimed |
| WO-2015149131-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2015-10-08 | — | — | WO | claimed |
| US-12435078-B2 | Pyridazinones and methods of use thereof | GFB (ABC), LLC (US) | 2025-10-07 | — | — | US | disclosed |
| EP-4605364-A1 | PROCESS FOR THE PREPARATION OF 4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL GRIGNARD COMPOUND AND DERIVATIVES THEREOF | BASF Agro B.V. (NL) | 2025-08-27 | — | — | EP | disclosed |
| CN-120051451-A | Process for preparing 4-chloro-2- (trifluoromethyl) phenyl grignard compounds and derivatives thereof | 巴斯夫农业公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-118255659-A | Preparation method of 2-trifluoromethyl benzoyl chloride and derivatives thereof | 辽宁天予化工有限公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2024083545-A1 | PROCESS FOR THE PREPARATION OF 4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL GRIGNARD COMPOUND AND DERIVATIVES THEREOF | BASF Agro B.V. (NL) | 2024-04-25 | — | — | WO | disclosed |
| CN-113302185-B | Benzofuran-6-carboxamide derivatives, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-115677635-B | Orange ketone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2024-04-09 | — | — | CN | disclosed |
| EP-0968177-A1 | METHOD FOR PRODUCING AROMATIC NITRILES | Bayer Aktiengesellschaft (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037058-A1 | METHOD FOR PRODUCING AROMATIC NITRILES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-08-27 | — | — | WO | disclosed |
| CN-1016868-B | Process for preparing 5-aralkyl-4-alkoxy-2 (5H) -furanone | SCHWABE WILLMAR GMBH & CO (DE) | 1992-06-03 | — | — | CN | disclosed |
| US-5041683-A | Nuclear-fluorinated trifluoromethylbenzaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| EP-0247320-B1 | 5-ARYLALKYL-4-ALKOXY-2(5H)-FURANONES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION AS WELL AS THEIR APPLICATION AS THERAPEUTICALLY ACTIVE INGREDIENTS | SCHWABE WILLMAR GMBH & CO (DE) | 1990-12-27 | — | — | EP | disclosed |
| US-4855320-A | ANTICONVULSANTS, ANTIEPILEPTICS | DR. WILLMAR SCHWABE GMBH & COMPANY (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0247320-A2 | 5-Arylalkyl-4-alkoxy-2(5H)-furanones, intermediates and process for their preparation as well as their application as therapeutically active ingredients | Dr. Willmar Schwabe GmbH & Co. (DE) | 1987-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435078-B2 | Pyridazinones and methods of use thereof | PDXK, ATP6V1B1, REN | TDP1 1811/4885ERN1 4529/4885RAB9A 3018/4885 |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | VIP, PEPD, NRDC | TDP1 4681/4885ERN1 1340/4885RAB9A 3902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.