Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.37 |
| ▸ | KDM6B | O15054 | 3/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.37 |
| ▸ | HK1 | P19367 | 2/20 | 0.37 |
| ▸ | HK2 | P52789 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL5827542 | 0.86 | TDP1 (0.44) | KDM4CKDM6BSLC5A2HK1HK2 | |
| SCHEMBL30465694 | 0.80 | KDM4C (0.51) | KDM4CKDM6BKDM4EMEN1KDM4A | |
| SCHEMBL123203 | 0.80 | KDM4C (0.51) | KDM4CKDM6BKDM4EMEN1KDM4A | |
| SCHEMBL8973945 | 0.77 | PYGL (0.43) | SLC5A2 | |
| Acetic Acid SCHEMBL16666943 | 0.77 | KDM4C (0.49) | KDM4CKDM6BKDM4EMEN1KDM4A | |
| Ribose (Furanose) SCHEMBL19717961 | 0.76 | NAPRT (0.53) | HK1HK2ALDH1A1MAPT | |
| Ribose (Furanose) SCHEMBL502577 | 0.75 | ALDH1A1 (0.58) | HK1HK2ALDH1A1THRBKMT2A | |
| Ribose (Furanose) SCHEMBL17479515 | 0.74 | TDP1 (0.47) | KDM4EALDH1A1MAPTTDP1 | |
| Ribose (Furanose) SCHEMBL19475127 | 0.73 | TSHR (0.39) | SLC5A2HK1HK2KDM4E | |
| Ribose (Furanose) SCHEMBL8953940 | 0.72 | NPC1 (0.48) | KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11633414-B2 | Nicotinoyl riboside compositions and methods of use | CORNELL UNIVERSITY (US) | 2023-04-25 | — | — | US | disclosed |
| US-20210353657-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2021-11-18 | — | — | US | disclosed |
| US-11077129-B2 | Nicotinoyl riboside compositions and methods of use | CORNELL UNIVERSITY (US) | 2021-08-03 | — | — | US | disclosed |
| EP-3730507-A1 | NICOTINOYL RIBOSIDE AND NICOTINAMIDE RIBOSIDE COMPOSITIONS FOR USE IN REDUCING TOXICITY INDUCED BY HMG-COA REDUCTASE INHIBITORS | Cornell Research Foundation, Inc. (US) | 2020-10-28 | — | — | EP | disclosed |
| US-20200289535-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL UNIVERSITY | 2020-09-17 | — | — | US | disclosed |
| US-10668096-B2 | Nicotinoyl riboside compositions and methods of use | CORNELL UNIVERSITY (US) | 2020-06-02 | — | — | US | disclosed |
| EP-3369738-B1 | METHOD FOR MAKING NICOTINOYL RIBOSIDES AND NICOTINAMIDE BETA-RIBOSIDE | CORNELL RES FOUNDATION INC (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20190192542-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL UNIVERSITY | 2019-06-27 | — | — | US | disclosed |
| US-10206940-B2 | Nicotinoyl riboside compositions and methods of use | CORNELL UNIVERSITY (US) | 2019-02-19 | — | — | US | disclosed |
| EP-3369738-A1 | NICOTINYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | Cornell Research Foundation, Inc. (US) | 2018-09-05 | — | — | EP | disclosed |
| EP-1957086-B1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL RES FOUNDATION INC (US) | 2018-05-02 | — | — | EP | disclosed |
| US-20160310517-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL UNIVERSITY | 2016-10-27 | — | — | US | disclosed |
| US-9321797-B2 | Nicotinoyl riboside compositions and methods of use | CORNELL UNIVERSITY (US) | 2016-04-26 | — | — | US | disclosed |
| US-9000147-B2 | Nicotyl riboside compositions and methods of use | CORNELL UNIVERSITY (US) | 2015-04-07 | — | — | US | disclosed |
| US-20150072950-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL UNIVERSITY | 2015-03-12 | — | — | US | disclosed |
| US-20120172584-A1 | NICOTYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2012-07-05 | — | — | US | disclosed |
| US-8106184-B2 | Nicotinoyl riboside compositions and methods of use | CORNELL UNIVERSITY (US) | 2012-01-31 | — | — | US | disclosed |
| EP-1957086-A2 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL RESEARCH FOUNDATION, INC. (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007061798-A2 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-05-31 | — | — | WO | disclosed |
| US-20070117765-A1 | Nicotinoyl riboside compositions and methods of use | CORNELL RESEARCH FOUNDATION INC. | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172584-A1 | NICOTYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | NNT, NAMPT, NAPRT | KDM4C 1477/4885KDM6B 1948/4885SLC5A2 872/4885 |
| US-11077129-B2 | Nicotinoyl riboside compositions and methods of use | NNT, CD38, NAMPT | KDM4C 940/4885KDM6B 1019/4885SLC5A2 641/4885 |
| US-20160310517-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | NADK, NNT, CD38 | KDM4C 886/4885KDM6B 1115/4885SLC5A2 627/4885 |
| US-20070117765-A1 | Nicotinoyl riboside compositions and methods of use | NNT, CD38, NAMPT | KDM4C 940/4885KDM6B 1019/4885SLC5A2 641/4885 |
| US-20190192542-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | NNT, CD38, NAMPT | KDM4C 940/4885KDM6B 1019/4885SLC5A2 641/4885 |
| US-20200289535-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | NNT, CD38, NAMPT | KDM4C 940/4885KDM6B 1019/4885SLC5A2 641/4885 |
| US-10668096-B2 | Nicotinoyl riboside compositions and methods of use | NNT, CD38, NAMPT | KDM4C 940/4885KDM6B 1019/4885SLC5A2 641/4885 |
| US-20210353657-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | NNT, CD38, NAMPT | KDM4C 940/4885KDM6B 1019/4885SLC5A2 641/4885 |
| US-20150072950-A1 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | NNT, CD38, NAMPT | KDM4C 940/4885KDM6B 1019/4885SLC5A2 641/4885 |
| US-11633414-B2 | Nicotinoyl riboside compositions and methods of use | NNT, CD38, NAMPT | KDM4C 940/4885KDM6B 1019/4885SLC5A2 641/4885 |
| US-10206940-B2 | Nicotinoyl riboside compositions and methods of use | NADK, NNT, CD38 | KDM4C 886/4885KDM6B 1115/4885SLC5A2 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.