Ribose (Furanose)

SCHEMBL19475127

CC(=O)c1ccncc1C(=O)N(C(C)=O)C(C)=O.OC[C@H]1OC(O)[C@H](O)[C@@H]1O

nearest known ligand 0.39

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	1/20	0.39

▸	SLC28A3	Q9HAS3	4/20	0.35

▸	HK1	P19367	2/20	0.32

▸	HK2	P52789	2/20	0.32

▸	KDM4E	B2RXH2	1/20	0.32

▸	LMNA	P02545	1/20	0.32

▸	CYP2D6	P10635	1/20	0.32

▸	CYP2C19	P33261	1/20	0.32

▸	SLC5A2	P31639	2/20	0.32

▸	CD69	Q07108	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Ribose (Furanose) SCHEMBL5827542	0.74	TDP1 (0.44)	HK1HK2KDM4ESLC5A2
Ribose (Furanose) SCHEMBL502905	0.73	KDM4C (0.37)	HK1HK2KDM4ESLC5A2
Ribose (Furanose) SCHEMBL17479515	0.73	TDP1 (0.47)	TSHRKDM4ELMNA
Ribose (Furanose) SCHEMBL502608	0.70	TSHR (0.43)	TSHRHK1HK2KDM4ECYP2C19
SCHEMBL8973945	0.69	PYGL (0.43)	SLC5A2
Ribose (Furanose) SCHEMBL19717961	0.67	NAPRT (0.53)	TSHRHK1HK2CYP2D6CYP2C19
SCHEMBL5878336	0.67	UMPS (0.44)	TSHRKDM4ELMNASLC5A2
SCHEMBL28317597	0.67	TDP1 (0.50)	KDM4ELMNACYP2C19
Ribose (Furanose) SCHEMBL502577	0.66	ALDH1A1 (0.58)	HK1HK2LMNA
Ribose (Furanose) SCHEMBL25392429	0.66	F7 (0.52)	HK1HK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017184885-A1	USE OF NICOTINIC ACID RIBOSIDE OR NICOTINAMIDE RIBOSITE DERIVATIVES, AND REDUCED DERIVATIVES THEREOF, AS NAD+INCREASING PRECURSORS	ChromaDex Inc. (US)	2017-10-26	—	—	WO	disclosed