Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 9/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 9/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880369 | 0.74 | — | — | |
| SCHEMBL2183970 | 0.74 | C5AR1 (0.43) | L3MBTL1LMNAALDH1A1HPGD | |
| SCHEMBL13737664 | 0.73 | SIGMAR1 (0.36) | L3MBTL1ALOX5 | |
| SCHEMBL566741 | 0.69 | AGER (0.49) | L3MBTL1DCUN1D1LMNA | |
| SCHEMBL29372829 | 0.69 | UBE2M (0.42) | UBE2MDCUN1D1 | |
| SCHEMBL785128 | 0.68 | GRIN2B (0.60) | ALDH1A1GRIN2B | |
| SCHEMBL10320551 | 0.67 | YTHDC1 (0.54) | ALDH1A1GRIN2B | |
| SCHEMBL385070 | 0.67 | YTHDC1 (0.54) | ALDH1A1GRIN2B | |
| SCHEMBL11117786 | 0.66 | OPRK1 (0.48) | PKM | |
| SCHEMBL16858848 | 0.66 | LAP3 (0.42) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378409-B2 | Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |