Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.74 |
| ▸ | FPGS | Q05932 | 2/20 | 0.73 |
| ▸ | GART | P22102 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | ATIC | P31939 | 4/20 | 0.48 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9486835 | 0.99 | SOST (0.73) | SOSTFPGSGARTLMNADHFR | |
| SCHEMBL7928061 | 0.95 | SOST (0.69) | SOSTFPGSGARTLMNADHFR | |
| SCHEMBL50298 | 0.94 | SOST (0.78) | SOSTFPGSGARTLMNADHFR | |
| SCHEMBL716106 | 0.94 | SOST (0.78) | SOSTFPGSGARTLMNADHFR | |
| SCHEMBL3953439 | 0.94 | SOST (0.78) | SOSTFPGSGARTLMNADHFR | |
| SCHEMBL15121249 | 0.94 | SOST (0.78) | SOSTFPGSGARTLMNADHFR | |
| SCHEMBL28469783 | 0.93 | SOST (0.77) | SOSTFPGSGARTLMNADHFR | |
| SCHEMBL27708884 | 0.93 | SOST (0.77) | SOSTFPGSGARTLMNADHFR | |
| SCHEMBL28206357 | 0.88 | SOST (0.79) | SOSTFPGSGARTLMNADHFR | |
| SCHEMBL4334665 | 0.88 | SOST (0.76) | SOSTFPGSGARTLMNADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250352605-A1 | DIETARY SUPPLEMENTS FOR MOOD SUPPORT | MELALEUCA INC (US) | 2025-11-20 | — | — | US | claimed |
| EP-4516303-A1 | COMPOSITION INCLUDING TEUPOLIOSIDE AND INOSITOL | IDI Integratori Dietetici Italiani S.r.l. (IT) | 2025-03-05 | — | — | EP | claimed |
| CN-113874001-B | Vitamin and mineral soft capsule formulation comprising vitamin C in ascorbate form | 拜耳消费者护理股份有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-113874001-A | Vitamin and mineral soft capsule formulation comprising vitamin C in the form of ascorbate | 拜耳消费者护理股份有限公司 | 2021-12-31 | — | — | CN | claimed |
| EP-4518690-B1 | A MICRONUTRIENT MIXTURE AND PHARMACEUTICAL COMPOSITION COMPRISING THE MICRONUTRIENT MIXTURE | RATH MATTHIAS W (US) | 2026-02-04 | — | — | EP | disclosed |
| US-20250352605-A1 | DIETARY SUPPLEMENTS FOR MOOD SUPPORT | MELALEUCA INC (US) | 2025-11-20 | — | — | US | disclosed |
| US-20250352596-A1 | DIETARY SUPPLEMENTS FOR MOOD SUPPORT | MELALEUCA INC (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4518690-A1 | A MICRONUTRIENT MIXTURE AND METHOD OF TREATING ESTROGEN RELATED COMPLICATIONS USING THE MICRONUTRIENT MIXTURE | Rath, Matthias W. (US) | 2025-03-12 | — | — | EP | disclosed |
| EP-4516303-A1 | COMPOSITION INCLUDING TEUPOLIOSIDE AND INOSITOL | IDI Integratori Dietetici Italiani S.r.l. (IT) | 2025-03-05 | — | — | EP | disclosed |
| CN-118844634-A | Co-delivery of calcium 5-methyltetrahydrofolate and vitamin D3Double emulsion gel of (2) and preparation method and application thereof | 华南农业大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-113874001-B | Vitamin and mineral soft capsule formulation comprising vitamin C in ascorbate form | 拜耳消费者护理股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-112641788-B | Use of 5-methyltetrahydrofolate compositions for improving sleep | 连云港金康和信药业有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-112641788-A | Application of 5-methyltetrahydrofolic acid composition for improving sleep | 连云港金康和信药业有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-112294821-A | Application of 5-methyltetrahydrofolic acid and composition thereof | 连云港金康和信药业有限公司 | 2021-02-02 | — | — | CN | disclosed |
| US-10849905-B2 | Stable 5-methyltetrahydrofolate formulations to moderate methylenetetrahydrofolate reductase associated polymorphisms | LA VITA COMPOUNDING PHARMACY (US) | 2020-12-01 | — | — | US | disclosed |
| US-10406159-B2 | Stable 5-methyltetrahydrofolate formulations to moderate methylenetetrahydrofolate reductase associated polymorphisms | LA VITA COMPOUNDING PHARMACY (US) | 2019-09-10 | — | — | US | disclosed |
| US-20180000823-A1 | STABLE 5-METHYLTETRAHYDROFOLATE FORMULATIONS TO MODERATE METHYLENETETRAHYDROFOLATE REDUCTASE ASSOCIATED POLYMORPHISMS | LA VITA COMPOUNDING PHARMACY LLC | 2018-01-04 | — | — | US | disclosed |
| WO-2016123076-A1 | STABLE 5-METHYLTRAHYDROFOLATE FORMULATIONS TO MODERATE METHYLENETETRAHYDROFOLATE REDUCTASE ASSOCIATED POLYMORPHISMS | LA VITA COMPOUNDING PHARMACY (US) | 2016-08-04 | — | — | WO | disclosed |
| US-5223500-A | Liver disorders, antitumor, anticarcinogenic agents | BIORESEARCH S.P.A. (IT) | 1993-06-29 | — | — | US | disclosed |
| US-5124452-A | Reduction of folic acid; methylation separation; purification; reducing agent stabilizer | BIORESEARCH S.P.A. (IT) | 1992-06-23 | — | — | US | disclosed |