Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033614 | 0.78 | PTGES (0.38) | ALDH1A1RORCMEN1KMT2AMAOA | |
| SCHEMBL5029381 | 0.78 | SLC6A4 (0.38) | SLC6A2SLC6A4RORCSLC18A3YTHDC1 | |
| SCHEMBL5033608 | 0.78 | PTGES (0.38) | ALDH1A1RORCMEN1KMT2AMAOA | |
| SCHEMBL17440250 | 0.77 | CTSD (0.40) | ALDH1A1KDM1AMEN1KMT2AMAOA | |
| SCHEMBL28810381 | 0.73 | SLC6A2 (0.38) | ALDH1A1SLC6A2SLC6A4SLC18A3CA2 | |
| SCHEMBL372240 | 0.68 | YTHDC1 (0.51) | ALDH1A1KDM1ASLC6A2SLC6A4CA2 | |
| SCHEMBL372241 | 0.68 | YTHDC1 (0.51) | ALDH1A1KDM1ASLC6A2SLC6A4CA2 | |
| SCHEMBL13280564 | 0.67 | TRPM8 (0.46) | ALDH1A1KDM1ASLC6A2SLC6A4CA2 | |
| Hydrochloric Acid SCHEMBL30335838 | 0.66 | YTHDC1 (0.50) | ALDH1A1KDM1ASLC6A2SLC6A4CA2 | |
| SCHEMBL10575235 | 0.66 | SLC18A3 (0.46) | ALDH1A1SLC6A2SLC6A4SLC18A3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378409-B2 | Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-20050054626-A1 | Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054626-A1 | Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity | CCL11, CCR1, CCR2 | ALDH1A1 827/4885KDM1A 3865/4885SLC6A2 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.