Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028334 | 0.77 | SCN4A (0.35) | ALDH1A1LMNACYP3A4 | |
| SCHEMBL3108980 | 0.73 | ACHE (0.39) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL5029804 | 0.72 | NOS2 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL12517837 | 0.69 | FFAR4 (0.41) | FFAR4ALDH1A1GAAMAPTRAPGEF4 | |
| SCHEMBL5552255 | 0.68 | KDM4E (0.32) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL2478476 | 0.68 | NOS3 (0.33) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL105712 | 0.67 | TSHR (0.38) | ALDH1A1LMNACYP3A4 | |
| SCHEMBL15737465 | 0.67 | — | — | |
| SCHEMBL5554342 | 0.65 | NOS2 (0.33) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL105711 | 0.65 | ACHE (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |