Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032656 | 0.83 | PPARG (0.41) | PPARGPPARACYP17A1MMP1MMP2 | |
| SCHEMBL3748687 | 0.82 | NR1D1 (0.36) | — | |
| SCHEMBL5374479 | 0.81 | CTSS (0.38) | — | |
| SCHEMBL8090953 | 0.79 | ATM (0.39) | MAPTTDP1 | |
| SCHEMBL8091529 | 0.78 | CTSS (0.39) | — | |
| SCHEMBL7516386 | 0.77 | PTPN1 (0.41) | ITGB3ITGA2BHDAC8 | |
| SCHEMBL92706 | 0.77 | ACACB (0.38) | — | |
| SCHEMBL15044629 | 0.77 | ACACB (0.38) | — | |
| SCHEMBL12761956 | 0.77 | NR1D1 (0.34) | — | |
| SCHEMBL15388283 | 0.76 | NR1D1 (0.52) | PPARGPPARAMMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176339-A1 | NEUTRAL LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2008-07-24 | — | — | US | disclosed |
| US-20080176339-A1 | NEUTRAL LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2008-07-24 | — | — | US | disclosed |
| US-20070166228-A1 | Neutral labeling reactants and conjugates derived thereof | WALLAC OY (FI) | 2007-07-19 | — | — | US | disclosed |
| US-20070166228-A1 | Neutral labeling reactants and conjugates derived thereof | WALLAC OY (FI) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166228-A1 | Neutral labeling reactants and conjugates derived thereof | NAAA, DNPEP, PAM | PPARG 1303/4885PPARA 1351/4885CYP17A1 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.