Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 5/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15388283 | 0.89 | NR1D1 (0.52) | NR1D1NR1H3ITGA4ITGB7KMT2A | |
| SCHEMBL5033940 | 0.87 | NR1D1 (0.36) | NR1D1NR1H3NPC1TP53RAB9A | |
| SCHEMBL9924678 | 0.85 | NR1D1 (0.48) | NR1D1NR1H3ITGA4ITGB7KMT2A | |
| SCHEMBL5032656 | 0.84 | PPARG (0.41) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL7804379 | 0.83 | NR1D1 (0.50) | NR1D1NR1H3ITGA4ITGB7KMT2A | |
| SCHEMBL8090953 | 0.82 | ATM (0.39) | NR1D1ITGA4ITGB7KMT2AMEN1 | |
| SCHEMBL13014185 | 0.78 | NR1D1 (0.66) | NR1D1NR1H3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13014193 | 0.78 | NR1D1 (0.66) | NR1D1NR1H3CRHBPCRHR2ALDH1A1 | |
| SCHEMBL15388528 | 0.77 | NR1D1 (0.48) | NR1D1NR1H3MMP1MMP2MMP9 | |
| SCHEMBL17714014 | 0.77 | ITGA4 (0.56) | NR1D1NR1H3ITGA4ITGB7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176339-A1 | NEUTRAL LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2008-07-24 | — | — | US | disclosed |
| US-20080176339-A1 | NEUTRAL LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2008-07-24 | — | — | US | disclosed |
| WO-2007082996-A1 | NEUTRAL LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2007-07-26 | — | — | WO | disclosed |
| US-20070166228-A1 | Neutral labeling reactants and conjugates derived thereof | WALLAC OY (FI) | 2007-07-19 | — | — | US | disclosed |
| US-20070166228-A1 | Neutral labeling reactants and conjugates derived thereof | WALLAC OY (FI) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166228-A1 | Neutral labeling reactants and conjugates derived thereof | NAAA, DNPEP, PAM | NR1D1 4118/4885NR1H3 4182/4885ITGA4 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.