SCHEMBL503448

SCHEMBL503448

CC(C)c1cc(-c2ccc(-c3ccc(O)cc3)cc2)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.56
MGLL Q99685 1/20 0.50
ESR1 P03372 13/20 0.47
ESR2 Q92731 11/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
GABRA1 P14867 1/20 0.45
GABRB2 P47870 1/20 0.45
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
ABL1 P00519 1/20 0.43
ABCB1 P08183 1/20 0.43
BCR P11274 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392149 1.00 ALOX5 (0.56) ALOX5MGLLESR1ESR2CA1
SCHEMBL4395181 0.91 CA1 (0.54) ALOX5CA1CA2GABRA1GABRB2
SCHEMBL19842185 0.88 ALOX5 (0.56) ALOX5MGLLESR1ESR2MEN1
SCHEMBL7081272 0.86 CA1 (0.50) ALOX5MGLLESR1ESR2CA1
SCHEMBL8714891 0.86 ALOX5 (0.57) ALOX5ESR1ESR2CA1CA2
Hydroquinone SCHEMBL11207604 0.85 GABRA1 (0.50) ALOX5ESR1ESR2CA1CA2
SCHEMBL16581399 0.83 APP (0.56) ALOX5ESR1ESR2CA1CA2
SCHEMBL2720122 0.82 RORC (0.54) ALOX5MGLLESR1ESR2MEN1
SCHEMBL22500129 0.82 RORC (0.54) ALOX5MGLLESR1ESR2MEN1
SCHEMBL30017397 0.82 ALOX5 (0.53) ALOX5ESR1ESR2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1375461-B1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME HONSHU CHEMICAL IND (JP) 2009-08-05 EP claimed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
US-20230018132-A1 REVERSIBLY THERMOCHROMIC AQUEOUS INKJET PRINTER INK COMPOSITION, INKJET PRINTER AND INK CARTRIDGE USING THE SAME RISO TECHNOLOGIES CORPORATION (JP) 2023-01-19 US disclosed
US-20220251406-A1 AQUEOUS INK COMPOSITION FOR REVERSIBLY THERMOCHROMIC WRITING INSTRUMENT, AND REFILL AND AQUEOUS BALLPOINT PEN INCORPORATING AQUEOUS INK COMPOSITION FOR REVERSIBLY THERMOCHROMIC WRITING INSTRUMENT KABUSHIKI KAISHA PILOT CORPORATION (ALSO TRADING AS PILOT CORPORATION) (JP) 2022-08-11 US disclosed
US-20220169919-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2022-06-02 US disclosed
EP-3954745-A1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME Kabushiki Kaisha Pilot Corporation (also trading as Pilot Corporation) (JP) 2022-02-16 EP disclosed
EP-3950068-A1 REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME THE PILOT INK CO., LTD. (JP) 2022-02-09 EP disclosed
WO-2020218134-A1 METHOD FOR PRODUCING TETRACARBOXYLIC ACID DIANHYDRIDE 本州化学工業株式会社 2020-10-29 WO disclosed
EP-2383265-A1 METHOD FOR MANUFACTURING TRIMELLITIC ANHYDRIDE ARYL ESTER Honshu Chemical Industry Co., Ltd. (JP) 2011-11-02 EP disclosed
US-20090306329-A1 NOVEL ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, NOVEL POLYESTERIMIDE PRECURSOR DERIVED THEREFROM, AND POLYESTERIMIDE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-12-10 US disclosed
US-20090306329-A1 NOVEL ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, NOVEL POLYESTERIMIDE PRECURSOR DERIVED THEREFROM, AND POLYESTERIMIDE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-12-10 US disclosed
EP-1375461-B1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME HONSHU CHEMICAL IND (JP) 2009-08-05 EP disclosed
CN-101400665-A Method for producing epoxy compound SUMITOMO CHEMICAL CO (JP) 2009-04-01 CN disclosed
US-20090054669-A1 Process For Producing Epoxy Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-26 US disclosed
EP-1995245-A1 METHOD FOR PRODUCING EPOXY COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-11-26 EP disclosed
US-6872858-B2 Diphenol and process for producing the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2005-03-29 US disclosed
US-20040049086-A1 Diphenol and process for producing the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2004-03-11 US disclosed
EP-1375461-A1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME Honshu Chemical Industry Co. Ltd. (JP) 2004-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306329-A1 NOVEL ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, NOVEL POLYESTERIMIDE PRECURSOR DERIVED THEREFROM, AND POLYESTERIMIDE NOTUM, WEE2, THEM6 ALOX5 404/4885MGLL 1042/4885ESR1 3617/4885
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB ALOX5 862/4885MGLL 2452/4885ESR1 4366/4885
US-20090054669-A1 Process For Producing Epoxy Compound RER1, AR, CYP1A1 ALOX5 609/4885MGLL 4752/4885ESR1 11/4885
US-20040049086-A1 Diphenol and process for producing the same CYP1A1, AHR, CYP2E1 ALOX5 907/4885MGLL 4427/4885ESR1 489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.