SCHEMBL5035872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5032679	0.90	LMNA (0.47)	LMNAMAPK1NPSR1HSD17B10ANO1
	SCHEMBL5032543	0.90	LMNA (0.48)	LMNAMAPK1ANO1GABRA2GABRB2
	SCHEMBL5034722	0.89	CYP3A4 (0.44)	LMNAMAPK1NPSR1HSD17B10GABRA2
	SCHEMBL5032622	0.88	FLT1 (0.40)	LMNAGABRB2CYP3A4MAPTNPC1
	SCHEMBL5032527	0.88	ALDH1A1 (0.46)	CYP3A4MAPTRAB9ATSHRHPGD
	SCHEMBL5039048	0.88	CYP3A4 (0.43)	LMNAMAPK1NPSR1CYP3A4MAPT
	SCHEMBL5035948	0.87	CYP3A4 (0.40)	LMNAMAPK1NPSR1HSD17B10CYP3A4
	SCHEMBL5032515	0.86	CYP3A4 (0.41)	NPSR1GABRA2GABRB2CYP3A4MAPT
	SCHEMBL5035199	0.86	CYP3A4 (0.39)	LMNAMAPK1NPSR1CYP3A4MAPT
	SCHEMBL5032643	0.85	FLT1 (0.38)	LMNACYP3A4MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.