SCHEMBL5032622

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5032527	0.92	ALDH1A1 (0.46)	FLT1FLT4KDRCYP3A4TSHR
	SCHEMBL5034722	0.90	CYP3A4 (0.44)	FLT1FLT4KDRCYP3A4TSHR
	SCHEMBL5032643	0.90	FLT1 (0.38)	FLT1FLT4KDRCYP3A4TSHR
	SCHEMBL5035149	0.89	ALDH1A1 (0.41)	FLT1FLT4KDRCYP3A4TSHR
	SCHEMBL5039048	0.88	CYP3A4 (0.43)	FLT1FLT4KDRCYP3A4TSHR
	SCHEMBL5035872	0.88	LMNA (0.48)	CYP3A4TSHRMAPTRAB9ALMNA
	SCHEMBL5034868	0.88	CYP3A4 (0.45)	CYP3A4TSHRMAPTRAB9AMEN1
	SCHEMBL5035146	0.88	FLT1 (0.39)	FLT1FLT4KDRCYP3A4MAPT
	SCHEMBL5032525	0.87	CRHR1 (0.39)	FLT1FLT4KDRCYP3A4TSHR
	SCHEMBL5035199	0.86	CYP3A4 (0.39)	FLT1FLT4KDRCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.