Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034993 | 0.91 | MEN1 (0.41) | RAB9AMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL5034757 | 0.87 | NPC1 (0.44) | RAB9AMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL5041310 | 0.84 | CES2 (0.37) | RAB9AMEN1KMT2ACES2CES1 | |
| SCHEMBL5035310 | 0.82 | HPGD (0.40) | MEN1KMT2APOLBCES2CES1 | |
| SCHEMBL5039139 | 0.81 | SMN1; SMN2 (0.40) | RAB9AL3MBTL1POLBCES2CES1 | |
| SCHEMBL5034732 | 0.78 | CNR1 (0.44) | RAB9AMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL5032563 | 0.77 | ALDH1A1 (0.47) | POLBCES2CES1GRM4ALDH1A1 | |
| SCHEMBL5032620 | 0.76 | HPGD (0.39) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL5035129 | 0.75 | TRPC3 (0.40) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL27664741 | 0.74 | HTR2C (0.47) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694673-B1 | THIAZOLE DERIVATES | HOFFMANN LA ROCHE (CH) | 2008-01-16 | — | — | EP | claimed |