Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035310 | 0.93 | HPGD (0.40) | HPGDMEN1KMT2AHSD17B10LMNA | |
| SCHEMBL5041390 | 0.90 | KMT2A (0.42) | HPGDMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL5034854 | 0.87 | HPGD (0.45) | HPGDMEN1KMT2AHSD17B10LMNA | |
| SCHEMBL5041310 | 0.83 | CES2 (0.37) | HPGDMEN1KMT2ALMNAKDM4E | |
| SCHEMBL5035949 | 0.83 | CYP3A4 (0.42) | HPGDMEN1KMT2ATSHRLMNA | |
| SCHEMBL5035948 | 0.83 | CYP3A4 (0.40) | HPGDMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL5034993 | 0.81 | MEN1 (0.41) | MEN1KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL5032562 | 0.80 | CRHBP (0.36) | MEN1KMT2ATSHRCRHBPCRHR2 | |
| SCHEMBL5032631 | 0.80 | CYP3A4 (0.37) | MEN1KMT2ATSHRLMNAKDM4E | |
| SCHEMBL5039110 | 0.80 | CYP3A4 (0.42) | MEN1KMT2APOLBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694673-B1 | THIAZOLE DERIVATES | HOFFMANN LA ROCHE (CH) | 2008-01-16 | — | — | EP | claimed |