Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036054 | 0.91 | RAB9A (0.39) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL5034732 | 0.87 | CNR1 (0.44) | MEN1KMT2AF10NPC1RAB9A | |
| SCHEMBL5032620 | 0.81 | HPGD (0.39) | MEN1KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL5035948 | 0.81 | CYP3A4 (0.40) | MEN1KMT2ATSHRLMNATDP1 | |
| SCHEMBL5035949 | 0.81 | CYP3A4 (0.42) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL5034899 | 0.79 | NLRP3 (0.38) | KMT2A | |
| SCHEMBL5041390 | 0.79 | KMT2A (0.42) | MEN1KMT2ATSHRLMNAEPHX2 | |
| SCHEMBL5032631 | 0.78 | CYP3A4 (0.37) | MEN1KMT2ATSHRLMNAL3MBTL1 | |
| SCHEMBL5034757 | 0.78 | NPC1 (0.44) | MEN1KMT2ANPC1RAB9ACNR1 | |
| SCHEMBL5032562 | 0.78 | CRHBP (0.36) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694673-B1 | THIAZOLE DERIVATES | HOFFMANN LA ROCHE (CH) | 2008-01-16 | — | — | EP | claimed |