Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035310 | 0.90 | HPGD (0.40) | CES2CES1SMN1; SMN2LMNAHPGD | |
| SCHEMBL5032672 | 0.86 | TLR7 (0.40) | CES2CES1SMN1; SMN2PTGS2LMNA | |
| SCHEMBL5039139 | 0.85 | SMN1; SMN2 (0.40) | CES2CES1SMN1; SMN2PTGS2LMNA | |
| SCHEMBL5036054 | 0.84 | RAB9A (0.39) | CES2CES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5032620 | 0.83 | HPGD (0.39) | LMNAHPGDKDM4EKMT2AMAPT | |
| SCHEMBL5039110 | 0.81 | CYP3A4 (0.42) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL5041390 | 0.81 | KMT2A (0.42) | LMNAHPGDKDM4EKMT2AMAPT | |
| SCHEMBL5032563 | 0.79 | ALDH1A1 (0.47) | CES2CES1SMN1; SMN2PTGS2LMNA | |
| SCHEMBL5035133 | 0.78 | HPGD (0.47) | SMN1; SMN2LMNAHPGDKDM4EKMT2A | |
| SCHEMBL5032679 | 0.77 | LMNA (0.47) | CES2CES1SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694673-B1 | THIAZOLE DERIVATES | HOFFMANN LA ROCHE (CH) | 2008-01-16 | — | — | EP | claimed |