Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535161 | 0.82 | NCEH1 (0.51) | NCEH1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4170309 | 0.79 | WDR5 (0.59) | NCEH1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11594011 | 0.77 | NCEH1 (0.50) | NCEH1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25799004 | 0.77 | NCEH1 (0.50) | NCEH1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1554945 | 0.76 | ALDH1A1 (0.42) | NCEH1HSD17B10CYP1A2MAPTTDP1 | |
| SCHEMBL13273691 | 0.76 | LDHA (0.58) | CYP1A2CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL11266839 | 0.76 | TSHR (0.52) | NCEH1HSD17B10CYP1A2MAPTTDP1 | |
| SCHEMBL11802841 | 0.73 | NCEH1 (0.50) | NCEH1HSD17B10KDM4EMAPTALDH1A1 | |
| SCHEMBL28006860 | 0.73 | CDC25B (0.60) | NCEH1HSD17B10KDM4ETDP1ALDH1A1 | |
| SCHEMBL3361843 | 0.73 | HSD17B10 (0.70) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402645-B2 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20070155923-A1 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |