Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046108 | 0.85 | PPARG (0.48) | PPARGNAAAMLYCDEPHX2DRD2 | |
| SCHEMBL5039508 | 0.84 | ROCK2 (0.44) | PPARGNAAAMLYCDEPHX2DRD2 | |
| SCHEMBL1852984 | 0.77 | MLYCD (0.51) | PPARGNAAAMLYCDEPHX2L3MBTL1 | |
| SCHEMBL5048757 | 0.77 | PPARG (0.44) | PPARGEPHX2HDAC3L3MBTL1PPARA | |
| SCHEMBL5047489 | 0.77 | PPARG (0.42) | PPARGEPHX2HDAC3L3MBTL1PPARA | |
| SCHEMBL5047162 | 0.76 | HDAC1 (0.44) | PPARGNAAAMLYCDEPHX2DRD2 | |
| SCHEMBL5039660 | 0.76 | HDAC1 (0.44) | PPARGNAAAMLYCDEPHX2DRD2 | |
| SCHEMBL1853396 | 0.76 | MLYCD (0.47) | PPARGNAAAMLYCDEPHX2L3MBTL1 | |
| SCHEMBL1852751 | 0.75 | PPARG (0.47) | PPARGNAAAMLYCDEPHX2DRD2 | |
| SCHEMBL1854711 | 0.72 | NAAA (0.48) | PPARGNAAAMLYCDEPHX2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | disclosed |