SCHEMBL503998

SCHEMBL503998

COc1cc(C(=O)O)cc(O)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TPMT P51580 6/20 1.00
▸ PTGS2 P35354 1/20 0.72
▸ CA12 O43570 3/20 0.66
▸ CA1 P00915 3/20 0.66
▸ CA2 P00918 3/20 0.66
▸ CA4 P22748 3/20 0.66
▸ CA6 P23280 3/20 0.66
▸ CA7 P43166 3/20 0.66
▸ CA9 Q16790 3/20 0.66
▸ CA14 Q9ULX7 3/20 0.66
▸ CA3 P07451 2/20 0.66
▸ CA5A P35218 2/20 0.66
▸ CA5B Q9Y2D0 2/20 0.66
▸ PKM P14618 1/20 0.66
▸ HTT P42858 1/20 0.59
▸ TUBB4A P04350 2/20 0.56
▸ TUBB P07437 2/20 0.56
▸ TUBA3C P0DPH7 2/20 0.56
▸ TUBA1B P68363 2/20 0.56
▸ TUBA4A P68366 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30240911 1.00 TPMT (1.00) TPMTPTGS2CA12CA1CA2
SCHEMBL22824410 0.90 TPMT (0.81) TPMTPTGS2CA12CA1CA2
SCHEMBL793706 0.88 TPMT (0.78) TPMTPTGS2CA12CA1CA2
3,4,5-Trimethoxybenzoic Acid SCHEMBL6592 0.88 TPMT (0.78) TPMTPTGS2CA12CA1CA2
SCHEMBL25359586 0.87 TPMT (0.77) TPMTPTGS2CA12CA1CA2
3,4,5-Trimethoxybenzoic Acid SCHEMBL11023602 0.86 TPMT (0.75) TPMTPTGS2CA12CA1CA2
3,4,5-Trimethoxybenzoic Acid SCHEMBL4080846 0.86 TPMT (0.75) TPMTPTGS2CA12CA1CA2
3,4,5-Trimethoxybenzoic Acid SCHEMBL10838612 0.86 TPMT (0.75) TPMTPTGS2CA12CA1CA2
3,4,5-Trimethoxybenzoic Acid SCHEMBL9739818 0.86 TPMT (0.75) TPMTPTGS2CA12CA1CA2
SCHEMBL12245712 0.85 TPMT (0.73) TPMTPTGS2HTTTUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 — — US claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 — — US claimed
EP-4477693-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS Korea Research Institute of Chemical Technology (KR) 2024-12-18 — — EP claimed
US-12076316-B2 Levorphanol prodrugs and processes for making and using them ZEVRA THERAPEUTICS INC. 2024-09-03 — — US claimed
WO-2023195794-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS 한국화학연구원 2023-10-12 — — WO claimed
US-20220096463-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2022-03-31 — — US claimed
US-11234975-B2 Levorphanol prodrugs and processes for making and using them KEMPHARM, INC. (US) 2022-02-01 — — US claimed
US-20200390757-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2020-12-17 — — US claimed
WO-2018191474-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM KEMPHARM, INC. (US) 2018-10-18 — — WO claimed
WO-2017189528-A1 CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING SAME Ecolab USA, Inc. (US) 2017-11-02 — — WO claimed
US-20120142719-A1 Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof ALTER DOMUS (US) LLC 2012-06-07 — — US claimed
US-20110002990-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF ALTER DOMUS (US) LLC 2011-01-06 — — US claimed
US-7196214-B2 Process for arylamine production XEROX CORPORATION (US) 2007-03-27 — — US claimed
US-20060111582-A1 Process for arylamine production XEROX CORPORATION (US) 2006-05-25 — — US claimed
EP-0534817-B1 Esterification process of salts of carboxylic acids RHODIA CHIMIE SA (FR) 1998-12-09 — — EP claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 — — US claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 — — US claimed
EP-0539274-B1 Method for the synthesis of aldehydes and of their derivatives RHONE POULENC CHIMIE (FR) 1996-04-10 — — EP claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 — — EP claimed
US-4756950-A Support, heat meltable ink layer comprising dye, saturated polyester MITSUBISHI PAPER MILLS, LTD. (JP) 1988-07-12 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200390757-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM OPRM1, OPRL1, OPRK1 TPMT 379/4885PTGS2 1209/4885CA12 1814/4885
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS FGB, NR4A1, CYP2E1 TPMT 3578/4885PTGS2 782/4885CA12 1007/4885
US-12076316-B2 Levorphanol prodrugs and processes for making and using them OPRM1, OPRL1, OPRK1 TPMT 379/4885PTGS2 1209/4885CA12 1814/4885
US-11234975-B2 Levorphanol prodrugs and processes for making and using them OPRM1, OPRL1, OPRK1 TPMT 379/4885PTGS2 1209/4885CA12 1814/4885
US-20060111582-A1 Process for arylamine production AOC2, UFM1, TYR TPMT 517/4885PTGS2 4018/4885CA12 4463/4885
US-20110002990-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF CYP2B6, CYP3A43, CYP2D6 TPMT 216/4885PTGS2 599/4885CA12 2215/4885
US-20120142719-A1 Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof CYP2B6, CYP3A43, CYP2D6 TPMT 216/4885PTGS2 599/4885CA12 2215/4885
US-20220096463-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM OPRM1, OPRL1, OPRK1 TPMT 379/4885PTGS2 1209/4885CA12 1814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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