Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CDC25C | P30307 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044496 | 0.95 | ATP4A (0.37) | MGLLALOX5CDC25ACDC25BCDC25C | |
| SCHEMBL5040330 | 0.93 | NTMT1 (0.40) | MGLLALOX5AVPR1BNPC1RAB9A | |
| SCHEMBL5044102 | 0.93 | MAPT (0.40) | MAPTNPC1RAB9AHTR2AHTR2C | |
| SCHEMBL5048696 | 0.92 | CDC25A (0.43) | MGLLMEN1KMT2AAVPR1BCDC25A | |
| SCHEMBL5039575 | 0.90 | AR (0.43) | MGLLMEN1KMT2AALOX5MAPT | |
| SCHEMBL5044042 | 0.90 | CDC25A (0.42) | MGLLMEN1KMT2AAVPR1BCDC25A | |
| SCHEMBL5047923 | 0.89 | ATP4A (0.38) | MGLLAVPR1BCDC25ACDC25BCDC25C | |
| SCHEMBL5047653 | 0.89 | ATP4A (0.38) | MGLLAVPR1BCDC25ACDC25BCDC25C | |
| SCHEMBL5049183 | 0.88 | NPC1 (0.40) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL5133506 | 0.88 | CPT2 (0.40) | MGLLCDC25ACDC25BCDC25CDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583762-B1 | PYRROLYL-THIAZOLES AND THEIR USE AS CB 1 RECEPTOR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | EP | claimed |