Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039799 | 0.87 | L3MBTL1 (0.53) | L3MBTL1THRATHRBNAAAMLYCD | |
| SCHEMBL1854949 | 0.86 | NAAA (0.51) | L3MBTL1THRATHRBNAAAMLYCD | |
| SCHEMBL5047873 | 0.85 | LMNA (0.54) | L3MBTL1THRATHRBNAAAMLYCD | |
| SCHEMBL5044615 | 0.85 | TMEM97 (0.60) | L3MBTL1THRATHRBNAAAMLYCD | |
| SCHEMBL5045657 | 0.83 | NAAA (0.71) | L3MBTL1THRATHRBNAAAMLYCD | |
| SCHEMBL5040097 | 0.82 | NPC1 (0.68) | L3MBTL1THRATHRBNAAAMLYCD | |
| SCHEMBL1855571 | 0.80 | NAAA (0.44) | L3MBTL1THRATHRBNAAAMLYCD | |
| SCHEMBL5044268 | 0.79 | NAAA (0.60) | L3MBTL1NAAATMEM97SIGMAR1CA2 | |
| SCHEMBL10595825 | 0.79 | L3MBTL1 (0.73) | L3MBTL1THRATHRBNAAAMLYCD | |
| SCHEMBL5694370 | 0.79 | L3MBTL1 (0.73) | L3MBTL1THRATHRBNAAAMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |