Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048875 | 0.87 | L3MBTL1 (0.54) | L3MBTL1TMEM97SIGMAR1NAAATHRA | |
| SCHEMBL1854601 | 0.87 | TMEM97 (0.51) | L3MBTL1TMEM97SIGMAR1NAAATHRA | |
| SCHEMBL5047873 | 0.84 | LMNA (0.54) | L3MBTL1TMEM97SIGMAR1NAAATHRA | |
| SCHEMBL5044615 | 0.84 | TMEM97 (0.60) | L3MBTL1TMEM97SIGMAR1NAAATHRA | |
| SCHEMBL5045657 | 0.82 | NAAA (0.71) | L3MBTL1TMEM97SIGMAR1NAAATHRA | |
| SCHEMBL5040097 | 0.81 | NPC1 (0.68) | L3MBTL1SIGMAR1NAAATHRATHRB | |
| SCHEMBL5049475 | 0.80 | NPC1 (0.56) | L3MBTL1TMEM97SIGMAR1NAAATHRA | |
| SCHEMBL5044268 | 0.78 | NAAA (0.60) | L3MBTL1TMEM97SIGMAR1NAAACA2 | |
| SCHEMBL5040331 | 0.78 | SMN1; SMN2 (0.54) | L3MBTL1TMEM97SIGMAR1NAAASMN1; SMN2 | |
| SCHEMBL5048884 | 0.77 | NAAA (0.55) | L3MBTL1TMEM97SIGMAR1NAAATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |