Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 11/20 | 0.42 |
| ▸ | IL2 | P60568 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237254 | 0.70 | HSD17B1 (0.54) | GRIN2BIL2HDAC6RORBALDH1A1 | |
| SCHEMBL5051437 | 0.69 | IL2 (0.66) | IL2MEN1KMT2AHDAC6RORB | |
| SCHEMBL5048874 | 0.67 | IL2 (0.47) | IL2MEN1MAPTKMT2ARORB | |
| SCHEMBL5048822 | 0.65 | HDAC6 (0.56) | IL2HDAC6RORBALDH1A1 | |
| SCHEMBL6254123 | 0.64 | NTRK1 (0.38) | IL2HDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL1198629 | 0.64 | MEN1 (0.49) | GRIN2BMEN1MAPTKMT2AGRIN1 | |
| SCHEMBL1764981 | 0.64 | ALDH1A1 (0.48) | HDAC6ALDH1A1GAAATMSMN1; SMN2 | |
| SCHEMBL1198760 | 0.63 | LOXL2 (0.48) | MEN1MAPTKMT2AHDAC6ALDH1A1 | |
| SCHEMBL23794687 | 0.62 | MAPT (0.64) | GRIN2BMEN1MAPTKMT2AGRIN1 | |
| SCHEMBL594373 | 0.62 | KDR (0.50) | IL2MEN1KMT2AHDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1983980-A2 | THIAZOLE AND THIADIAZOLE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | Synta Pharmaceuticals Corporation (US) | 2008-10-29 | — | — | EP | claimed |
| WO-2007087427-A2 | THIAZOLE AND THIADIAZOLE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | claimed |
| EP-1983980-A2 | THIAZOLE AND THIADIAZOLE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | Synta Pharmaceuticals Corporation (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007087427-A2 | THIAZOLE AND THIADIAZOLE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |