Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048822 | 0.77 | HDAC6 (0.56) | HDAC6IL2DGAT1ALDH1A1PIK3CD | |
| SCHEMBL5051437 | 0.71 | IL2 (0.66) | HDAC6IL2RORB | |
| SCHEMBL1764981 | 0.70 | ALDH1A1 (0.48) | HDAC6ALDH1A1SMN1; SMN2DYRK1ADYRK2 | |
| SCHEMBL5048966 | 0.70 | GRIN2B (0.42) | HDAC6IL2GRIN2BALDH1A1SMN1; SMN2 | |
| SCHEMBL594373 | 0.68 | KDR (0.50) | HDAC6IL2DGAT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13018928 | 0.68 | ALDH1A1 (0.49) | HDAC6ALDH1A1SMN1; SMN2DYRK1ADYRK2 | |
| SCHEMBL40156 | 0.68 | ADORA2A (0.49) | HDAC6ALDH1A1SMN1; SMN2RORBDYRK1A | |
| SCHEMBL1198760 | 0.67 | LOXL2 (0.48) | HDAC6ALDH1A1DYRK1ADYRK2 | |
| SCHEMBL6254123 | 0.66 | NTRK1 (0.38) | HDAC6IL2ALDH1A1SMN1; SMN2KMO | |
| SCHEMBL216900 | 0.66 | HSD17B1 (0.54) | HSD17B1HSD17B2HDAC6IL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087427-A2 | THIAZOLE AND THIADIAZOLE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |