Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913281 | 0.81 | ENPP2 (0.45) | ENPP2ALDH1A1KDM4EMGLL | |
| SCHEMBL483888 | 0.79 | MIF (0.67) | MIFALDH1A1KDM4EMEN1CYP3A4 | |
| SCHEMBL8764209 | 0.75 | P2RY6 (0.50) | MIFENPP2KDM4EMGLLP2RY6 | |
| Bitoscanate SCHEMBL11598436 | 0.74 | MIF (0.68) | MIFALDH1A1KDM4EMEN1CYP3A4 | |
| SCHEMBL8069515 | 0.74 | ENPP2 (0.50) | ENPP2ALDH1A1KDM4EMGLL | |
| SCHEMBL9701237 | 0.74 | MIF (0.54) | MIFALDH1A1MEN1CYP3A4MAPT | |
| SCHEMBL723373 | 0.74 | MIF (0.54) | MIFALDH1A1MEN1CYP3A4MAPT | |
| SCHEMBL8764056 | 0.73 | MIF (0.44) | MIFALDH1A1KDM4EMEN1CYP3A4 | |
| SCHEMBL7641390 | 0.72 | MEN1 (0.55) | ENPP2MEN1KMT2A | |
| SCHEMBL7641392 | 0.72 | MEN1 (0.55) | ENPP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452858-B1 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INT BV (NL) | 1997-07-16 | — | — | EP | claimed |
| EP-0452858-A2 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INTERNATIONAL B.V. (NL) | 1991-10-23 | — | — | EP | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-1392504-A4 | SENSOR SURFACES FOR DETECTING ANALYTES | AGILENT TECHNOLOGIES INC (US) | 2008-03-05 | — | — | EP | disclosed |
| US-7208322-B2 | Sensor surfaces for detecting analytes | AGILENT TECHNOLOGIES, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-7179659-B2 | Detection of preferential particles in sample; obtain sample, incubate with sensor and substrate, monitor and measure response, evaluate for presence of particle | AGILENT TECHNOLOGIES, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1165569-B1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES INC (US) | 2005-08-10 | — | — | EP | disclosed |
| US-6870065-B2 | Bifunctional boronic compound complexing reagents and complexes | CAMBREX BIO SCIENCE ROCKLAND, INC. (US) | 2005-03-22 | — | — | US | disclosed |
| EP-1392504-A1 | SENSOR SURFACES FOR DETECTING ANALYTES | Prolinx Incorporated (US) | 2004-03-03 | — | — | EP | disclosed |
| US-6630577-B2 | Useful for producing bioconjugates | PROLINX, INC. | 2003-10-07 | — | — | US | disclosed |
| US-20030105280-A1 | Bifunctional boronic compound complexing reagents and complexes | AHLEM CLARENCE N (US) | 2003-06-05 | — | — | US | disclosed |
| WO-1998005627-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND HIGHLY STABLE COMPLEXES | PROLINX, INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| US-5677431-A | Phenylboronic acid complexes for bioconjugate preparation | PROLINX, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| EP-0452858-B1 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INT BV (NL) | 1997-07-16 | — | — | EP | disclosed |
| US-5623055-A | Phenylboronic acid complexes derived from aminosalicylic acid for bioconjugate preparation | PROLINX, INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5594111-A | Phenylboronic acid complexes for bioconjugate preparation | PROLINX, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0741734-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020591-A1 | PHENYLBORONIC ACID COMPLEXES | PROLINX, INC. (US) | 1995-08-03 | — | — | WO | disclosed |
| US-5183653-A | BORONIC ACID ADDUCTS OF METAL DIOXIME COMPLEXES USEFUL IN LABELLING PROTEINS AND OTHER AMINE-CONTAINING COMPOUNDS | E. R. SQUIBB & SONS, INC. (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0452858-A2 | Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds | BRACCO INTERNATIONAL B.V. (NL) | 1991-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105280-A1 | Bifunctional boronic compound complexing reagents and complexes | CHN2, CFH, COG2 | MIF 2130/4885ENPP2 3274/4885ALDH1A1 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.