Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868121 | 0.88 | MAPK1 (0.50) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7868065 | 0.85 | MAPK1 (0.48) | MAPK1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7874778 | 0.79 | HDAC3 (0.48) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7879205 | 0.72 | EPHX2 (0.38) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6056911 | 0.71 | PDE5A (0.46) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6316630 | 0.71 | ROCK2 (0.62) | ROCK2ROCK1 | |
| SCHEMBL9781764 | 0.71 | TGM2 (0.51) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7873367 | 0.70 | TGM2 (0.49) | MAPK1SMN1; SMN2TGM2LMNA | |
| SCHEMBL8241346 | 0.69 | NPC1 (0.51) | HDAC3NPC1RAB9ATGM2 | |
| SCHEMBL9705390 | 0.69 | HTT (0.64) | MAPK1HDAC6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1929014-B1 | METHODS OF ALTERING AN IMMUNE RESPONSE INDUCED BY D-TYPE CPG OLIGODEOXYNUCLEOTIDES | US GOV HEALTH & HUMAN SERV (US) | 2014-08-13 | — | — | EP | disclosed |
| US-8470342-B2 | Methods of altering an immune response induced by CpG oligodeoxynucleotides | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-06-25 | — | — | US | disclosed |
| US-20080249056-A1 | Methods of Altering an Immune Response Induced by Cpg Oligodeoxynucleotides | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2008-10-09 | — | — | US | disclosed |
| EP-1929014-A1 | METHODS OF ALTERING AN IMMUNE RESPONSE INDUCED BY CPG OLIGODEOXYNUCLEOTIDES | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027718-A1 | METHODS OF ALTERING AN IMMUNE RESPONSE INDUCED BY CPG OLIGODEOXYNUCLEOTIDES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249056-A1 | Methods of Altering an Immune Response Induced by Cpg Oligodeoxynucleotides | CXCL10, CCL2, CXCR6 | MAPK1 3329/4885HDAC6 1845/4885HDAC3 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.