Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058959 | 0.80 | MAPT (0.51) | KEAP1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL5015698 | 0.76 | FPR2 (0.40) | KEAP1NFE2L2CTSKSCN9ACYP1A2 | |
| SCHEMBL5015677 | 0.75 | FPR2 (0.40) | KEAP1NFE2L2CTSKSCN9ACYP1A2 | |
| SCHEMBL5014111 | 0.70 | CTSS (0.43) | CTSKHPGDMAPTMEN1KMT2A | |
| SCHEMBL10045812 | 0.68 | MAPT (0.60) | MAPTMEN1KMT2AKLK7KLK5 | |
| SCHEMBL14744109 | 0.68 | HTT (0.43) | MAPTMEN1KMT2ALMNA | |
| SCHEMBL14737595 | 0.68 | HTT (0.43) | MAPTMEN1KMT2ALMNA | |
| SCHEMBL7893434 | 0.66 | MAPT (0.53) | KEAP1NFE2L2MAPTKLK7KLK5 | |
| SCHEMBL6129649 | 0.66 | TGM2 (0.55) | KEAP1NFE2L2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7759126 | 0.66 | MAPT (0.53) | KEAP1NFE2L2MAPTKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009942-A1 | HETEROAROMATIC-BASED PEPTIDE MACROCYCLES AS G-QUADRUPLEX LIGANDS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-01-24 | — | — | WO | disclosed |