Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015698 | 0.93 | FPR2 (0.40) | FPR2HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5014193 | 0.80 | CTSK (0.37) | MAPTCTSKATMCTSSITGB3 | |
| SCHEMBL5015675 | 0.79 | MAPT (0.59) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL5058970 | 0.75 | KEAP1 (0.38) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5015696 | 0.72 | MAPT (0.56) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL7893434 | 0.69 | MAPT (0.53) | MAPTTSHRKEAP1NFE2L2ITGB3 | |
| SCHEMBL7759126 | 0.69 | MAPT (0.53) | MAPTTSHRKEAP1NFE2L2ITGB3 | |
| SCHEMBL6129649 | 0.69 | TGM2 (0.55) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30600455 | 0.69 | MAPT (0.53) | MAPTTSHRKEAP1NFE2L2ITGB3 | |
| SCHEMBL6129662 | 0.69 | TGM2 (0.55) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009942-A1 | HETEROAROMATIC-BASED PEPTIDE MACROCYCLES AS G-QUADRUPLEX LIGANDS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-01-24 | — | — | WO | disclosed |