Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828909 | 0.90 | ALDH1A1 (0.56) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL2573164 | 0.90 | ALDH1A1 (0.56) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL9133437 | 0.88 | ALDH1A1 (0.54) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL9134133 | 0.88 | ALDH1A1 (0.54) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL9132558 | 0.88 | ALDH1A1 (0.54) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL9132688 | 0.88 | ALDH1A1 (0.54) | ALDH1A1ALOX15CA12CA1CA2 | |
| SCHEMBL1743540 | 0.85 | BCAT2 (0.44) | ALDH1A1ALOX15KDM4EHPGDMAPT | |
| SCHEMBL2073567 | 0.84 | KMT2A (0.42) | ALDH1A1ALOX15KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28305847 | 0.83 | AKR1C3 (0.50) | ALDH1A1KDM4ESMN1; SMN2MAPTAKR1C3 | |
| Tetramethylammonium Ion SCHEMBL9132602 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ALOX15CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102162-A1 | TGONOVEL HDAC INHIBITORS AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| CN-105820560-B | Molded article comprising polyamide resin composition | 旭化成株式会社 | 2021-12-03 | — | — | CN | disclosed |
| EP-2824069-B1 | SURFACE-TREATED CARBON NANOTUBE AND RESIN COMPOSITION | ASAHI CHEMICAL IND (JP) | 2021-09-22 | — | — | EP | disclosed |
| US-10479853-B2 | Surface-treated carbon nanotube and resin composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2019-11-19 | — | — | US | disclosed |
| US-9006454-B2 | Dihydroorotate dehydrogenase inhibitors | MERCK SERONO S.A. (CH) | 2015-04-14 | — | — | US | disclosed |
| EP-2824069-A1 | SURFACE-TREATED CARBON NANOTUBE AND RESIN COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2015-01-14 | — | — | EP | disclosed |
| EP-2414328-A2 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |
| US-20120028959-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | MERCK SERONO S.A. (CH) | 2012-02-02 | — | — | US | disclosed |
| US-20110046134-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | BISCHOFF ALEXANDER | 2011-02-24 | — | — | US | disclosed |
| US-7842696-B2 | Piperazine derivatives as inhibitors of stearoyl-CoA desaturase | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-30 | — | — | US | disclosed |
| WO-2010115736-A2 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | MERCK SERONO S.A. (CH) | 2010-10-14 | — | — | WO | disclosed |
| US-20090221583-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-03 | — | — | US | disclosed |
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |
| US-6291442-B1 | Pharmacological modulators of voltage-gated potassium ion channels | THE GENERAL HOSPITAL CORPORATION | 2001-09-18 | — | — | US | disclosed |
| EP-0513030-B1 | NEW CIS-PLATINUM COMPLEXES WITH CHELATING AMINES AND SULPHINYL CARBOXYLATES | BOEHRINGER MANNHEIM ITALIA (IT) | 1994-01-26 | — | — | EP | disclosed |
| US-5275827-A | Cis-platinum complexes with chelating amines and sulphinyl carboxylates | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-01-04 | — | — | US | disclosed |
| EP-0513030-A1 | NEW CIS-PLATINUM COMPLEXES WITH CHELATING AMINES AND SULPHINYL CARBOXYLATES. | BOEHRINGER MANNHEIM ITALIA (IT) | 1992-11-19 | — | — | EP | disclosed |
| US-5157097-A | Reacting aromatic tricarboxylic acids, diisocyanates, diamines and end-blocking compounds; high glass transition temperature, heat resistant, melt moldable | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-10-20 | — | — | US | disclosed |
| EP-0472421-A2 | Polyamide-imide resins and process of producing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-02-26 | — | — | EP | disclosed |
| WO-1991011450-A1 | NEW CIS-PLATINUM COMPLEXES WITH CHELATING AMINES AND SULPHINYL CARBOXYLATES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479853-B2 | Surface-treated carbon nanotube and resin composition | ACTN1, CD63, ACTN4 | ALDH1A1 3198/4885ALOX15 3500/4885CA12 1047/4885 |
| US-20110046134-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | ALDH1A1 969/4885ALOX15 211/4885CA12 4790/4885 |
| US-20120028959-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | DHODH, FH, DPYD | ALDH1A1 95/4885ALOX15 2287/4885CA12 2228/4885 |
| US-20090221583-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | ALDH1A1 969/4885ALOX15 211/4885CA12 4790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.