Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064949 | 0.74 | IMPDH2 (0.37) | — | |
| SCHEMBL7364092 | 0.74 | PDPK1 (0.47) | ADORA1ADORA2AADORA2BKDM4EMEN1 | |
| SCHEMBL3485241 | 0.73 | PARP1 (0.47) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5069316 | 0.71 | BRD4 (0.36) | ADORA1ADORA2APDPK1 | |
| SCHEMBL5065086 | 0.71 | IMPDH2 (0.44) | ADORA1ADORA2ASTK4STK3TMIGD3 | |
| SCHEMBL28457537 | 0.70 | ADORA2A (0.47) | ADORA1ADORA2AADORA2BKDM4EMEN1 | |
| SCHEMBL4563349 | 0.69 | XDH (0.51) | ADORA1ADORA2AADORA2BKMT2AALDH1A1 | |
| SCHEMBL10965948 | 0.68 | ADORA2A (0.45) | ADORA1ADORA2AADORA2BKDM4EMEN1 | |
| SCHEMBL4629034 | 0.68 | ALDH1A1 (0.53) | ADORA1ADORA2AADORA2BKDM4EMEN1 | |
| SCHEMBL5069269 | 0.68 | NPC1 (0.49) | ADORA1ADORA2AADORA2BKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261823-A1 | Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-10-23 | — | — | US | claimed |
| WO-2006076102-A2 | FLUORESCENT NUCLEOSIDE ANALOGS THAT MIMIC NATURALLY OCCURRING NUCLEOSIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | claimed |
| US-20080261823-A1 | Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-10-23 | — | — | US | disclosed |
| WO-2006076102-A2 | FLUORESCENT NUCLEOSIDE ANALOGS THAT MIMIC NATURALLY OCCURRING NUCLEOSIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261823-A1 | Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides | NSUN2, NSUN3, NCL | ADORA1 436/4885ADORA2A 243/4885ADORA2B 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.