Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779347 | 1.00 | PRKCA (0.49) | PRKCAFAAHTERTPTPN1PPARG | |
| SCHEMBL5066137 | 1.00 | PRKCA (0.49) | PRKCAFAAHTERTPTPN1PPARG | |
| SCHEMBL17780094 | 1.00 | PRKCA (0.49) | PRKCAFAAHTERTPTPN1PPARG | |
| SCHEMBL2779350 | 1.00 | PRKCA (0.49) | PRKCAFAAHTERTPTPN1PPARG | |
| SCHEMBL18206407 | 1.00 | PRKCA (0.49) | PRKCAFAAHTERTPTPN1PPARG | |
| SCHEMBL12435787 | 0.96 | MGLL (0.55) | FAAHPPARGPPARDPPARAHSD17B10 | |
| SCHEMBL23417025 | 0.92 | FAAH (0.56) | FAAHPPARGPPARDPPARAMAPT | |
| SCHEMBL27409126 | 0.91 | MGLL (0.43) | PRKCAFAAHMAPTKMT2APGR | |
| SCHEMBL1361856 | 0.91 | KMT2A (0.54) | PRKCAKMT2ALMNA | |
| SCHEMBL18218758 | 0.91 | KMT2A (0.54) | PRKCAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914223-A1 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | CRODA INTERNATIONAL plc (GB) | 2008-04-23 | — | — | EP | disclosed |
| US-6956059-B2 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | CRODA INTERNATIONAL, PLC (GB) | 2005-10-18 | — | — | US | disclosed |
| US-20040242663-A1 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | CRODA INTERNATIONAL, PLC (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1389180-A1 | ANTI-INFLAMMATORY AND IMMUNOMODULATORY AMINO ACID DERIVATIVES, THEIR PREPARATION AND USE | CRODA INTERNATIONAL plc (GB) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094764-A1 | ANTI-INFLAMMATORY AND IMMUNOMODULATORY AMINO ACID DERIVATIVES, THEIR PREPARATION AND USE | CRODA INTERNATIONAL PLC (GB) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242663-A1 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use | ARG1, IL6, IL4I1 | PRKCA 1995/4885FAAH 428/4885TERT 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.