Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363023 | 0.78 | METAP2 (0.45) | HSD17B10ALOX15KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5067767 | 0.76 | ALDH1A1 (0.41) | HSD17B10ALOX15KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10562583 | 0.76 | CYP2C9 (0.49) | HSD17B10KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7500143 | 0.74 | KDM4E (0.53) | HSD17B10ALOX15KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5068545 | 0.74 | HSD17B1 (0.52) | KDM4EALDH1A1MAPTHPGDADORA3 | |
| SCHEMBL5071237 | 0.73 | KMT2A (0.40) | KDM4EALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL5070312 | 0.72 | HSD17B1 (0.44) | HSD17B10KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL27659947 | 0.69 | ALDH1A1 (0.43) | HSD17B10KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL3208371 | 0.69 | MAPT (0.52) | HSD17B10ALOX15KDM4EALDH1A1ATM | |
| SCHEMBL5480782 | 0.69 | ATM (0.56) | HSD17B10ALOX15KDM4EALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234301-A1 | Alpha-4 Integrin Mediated Cell Adhesion Inhibitors for the Treatment or Prevention of Inflammatory Diseases | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234301-A1 | Alpha-4 Integrin Mediated Cell Adhesion Inhibitors for the Treatment or Prevention of Inflammatory Diseases | ITGB4, ITGA4, ICAM1 | HSD17B10 3097/4885ALOX15 496/4885KDM4E 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.