Sugi Predict

Sugi Predict / Compounds / SCHEMBL507097

SCHEMBL507097

SCHEMBL507097

Cc1ccc2nc(-c3ccccc3)sc2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 10/20 0.71
▸ KDM4E B2RXH2 6/20 0.71
▸ APP P05067 5/20 0.71
▸ RAB9A P51151 5/20 0.71
▸ GLA P06280 4/20 0.71
▸ GAA P10253 4/20 0.71
▸ NPC1 O15118 4/20 0.71
▸ SNCA P37840 1/20 0.68
▸ SMN1; SMN2 Q16637 7/20 0.66
▸ ALDH1A1 P00352 6/20 0.66
▸ HPGD P15428 5/20 0.66
▸ MEN1 O00255 3/20 0.66
▸ KMT2A Q03164 3/20 0.66
▸ PKM P14618 1/20 0.66
▸ LMNA P02545 3/20 0.62
▸ NFKB1 P19838 1/20 0.62
▸ NFKB2 Q00653 1/20 0.62
▸ RELA Q04206 1/20 0.62
▸ CASP3 P42574 1/20 0.57
▸ SENP8 Q96LD8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12422217 0.89 MAPT (0.81) MAPTKDM4EAPPRAB9AGLA
SCHEMBL14111242 0.88 MAPT (0.65) MAPTKDM4EAPPRAB9AGLA
SCHEMBL1100094 0.87 MAPT (0.60) MAPTKDM4EAPPRAB9AGLA
SCHEMBL13645798 0.87 MAPT (0.60) MAPTKDM4EAPPRAB9AGLA
SCHEMBL13645790 0.87 MAPT (0.60) MAPTKDM4EAPPRAB9AGLA
SCHEMBL2195913 0.87 MAPT (0.63) MAPTKDM4EAPPRAB9AGLA
SCHEMBL1987260 0.87 MAPT (0.63) MAPTKDM4EAPPRAB9AGLA
SCHEMBL13645860 0.86 MAPT (0.59) MAPTKDM4EAPPRAB9AGLA
SCHEMBL23954319 0.86 APP (0.58) MAPTKDM4EAPPRAB9AGLA
SCHEMBL507496 0.86 SMN1; SMN2 (0.71) MAPTKDM4EAPPRAB9AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841790-A Method for preparing 2-substituted benzothiazole derivatives by driving light 中国科学院大连化学物理研究所 2025-04-18 — — CN disclosed
EP-4307402-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2024-01-17 — — EP disclosed
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-01 — — US disclosed
CN-111793040-B Preparation method of 2-substituted benzothiazole 太原理工大学 2023-01-03 — — CN disclosed
US-20210095196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-01 — — US disclosed
US-20200377457-A1 MIF MODULATORS UNIV YALE (US) 2020-12-03 — — US disclosed
CN-111793040-A Preparation method of 2-substituted benzothiazole 太原理工大学 2020-10-20 — — CN disclosed
WO-2020123610-A1 COMPOUNDS AND METHODS FOR TREATING COPD AND/OR LUNG FIBROSIS YALE UNIVERSITY (US) 2020-06-18 — — WO disclosed
CN-109180590-A A method of Benzoheterocyclic compounds are quickly prepared using physical grinding method under room temperature solvent-free 福建医科大学 2019-01-11 — — CN disclosed
US-20170217974-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2017-08-03 — — US disclosed
US-20090099155-A1 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS ARRAY BIOPHARMA, INC. 2009-04-16 — — US disclosed
US-7255938-B2 Organic electroluminescent device and organic compound for use in organic electroluminescent device SANYO ELECTRIC CO., LTD. (JP) 2007-08-14 — — US disclosed
CN-1934088-A As 5-HT2c6-substituted 2,3,4, 5-tetrahydro-1H-benzo [ d ] receptor agonists]Aza * LILLY CO ELI (US) 2007-03-21 — — CN disclosed
CN-1303043-C Process for producing biaryl compound SUMITOMO CHEMICAL CO (JP) 2007-03-07 — — CN disclosed
EP-1720836-A1 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2006-11-15 — — EP disclosed
WO-2005082859-A1 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS ELI LILLY AND COMPANY (US) 2005-09-09 — — WO disclosed
CN-1642879-A Process for preparing diaryl compounds SUMITOMO CHEMICAL CO (JP) 2005-07-20 — — CN disclosed
US-20050096471-A1 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-05 — — US disclosed
EP-1473286-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-03 — — EP disclosed
US-4137228-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-01-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099155-A1 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS HTR2C, HTR5A, HTR4 MAPT 4341/4885KDM4E 1208/4885APP 2423/4885
US-20200377457-A1 MIF MODULATORS MIF, HMGB2, HMGB3 MAPT 3356/4885KDM4E 3588/4885APP 4268/4885
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE CHRM1, CHRM2, CHRM4 MAPT 4606/4885KDM4E 3767/4885APP 2850/4885
US-20210095196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, OSBP MAPT 2600/4885KDM4E 3361/4885APP 4517/4885
US-20170217974-A1 HEPATITIS B ANTIVIRAL AGENTS HAVCR2, ZC3HAV1, SLC10A1 MAPT 4656/4885KDM4E 1172/4885APP 1176/4885
US-20050096471-A1 Process for producing biaryl compound PPOX, CAT, TYR MAPT 3403/4885KDM4E 3428/4885APP 1198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.