SCHEMBL50727

SCHEMBL50727

[CH]=Cc1ccccc1-c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.43
ALDH1A1 P00352 5/20 0.39
CYP2A6 P11509 3/20 0.39
TSHR P16473 3/20 0.39
HSD17B10 Q99714 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 2/20 0.38
PTPN1 P18031 1/20 0.38
RXRA P19793 1/20 0.38
ALPL P05186 1/20 0.38
GAA P10253 1/20 0.38
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
NISCH Q9Y2I1 1/20 0.37
CYP1A2 P05177 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123180 0.82 TSHR (0.48) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL30618856 0.79 BACE1 (0.43) BACE1ALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL31177892 0.79 MEN1 (0.48) BACE1ALDH1A1CYP2A6TSHRTDP1
SCHEMBL548462 0.79 MEN1 (0.48) BACE1ALDH1A1CYP2A6TSHRTDP1
SCHEMBL2354617 0.79 BACE1 (0.43) BACE1ALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL25302086 0.79 ALDH1A1 (0.59) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL27953 0.79 ALDH1A1 (0.59) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL29350007 0.79 ALDH1A1 (0.59) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL6077039 0.77 ALDH1A1 (0.56) ALDH1A1CYP2A6TSHRHSD17B10TDP1
Bromide SCHEMBL7106161 0.77 ALDH1A1 (0.56) ALDH1A1CYP2A6TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131655-B1 METHOD FOR THE QUANTIFICATION OF PARASITE EGGS IN FECES MEP Equine Solutions LLC (US) 2020-12-02 EP claimed
EP-2404550-B1 Systems and methods of 4D electromagnetic tomographic (EMT) differential (dynamic) fused imaging EMIMAGING LTD (GB) 2015-11-11 EP claimed
CN-111201328-B Detection of recombinant enzyme polymerase amplification using double hapten probes 雅培诊断产品士嘉堡公司 2024-07-02 CN disclosed
CN-118086454-A Method for detecting dephosphorylation activity of T4 polynucleotide kinase 3' end, probe set and kit 深圳市真迈生物科技有限公司 2024-05-28 CN disclosed
CN-111527257-B Fabric treatment composition and method HBI品牌服饰企业有限公司 2022-01-28 CN disclosed
US-20210275806-A1 CATHETER SYSTEMS ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. 2021-09-09 US disclosed
US-11000684-B2 Catheter systems ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) 2021-05-11 US disclosed
CN-112384808-A Methods for mitigating drug target interference in anti-drug antibody (ADA) immunoassays 里珍纳龙药品有限公司 2021-02-19 CN disclosed
US-20200269038-A1 CATHETER SYSTEMS ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. 2020-08-27 US disclosed
CN-111527257-A Fabric treatment composition and method HBI品牌服饰企业有限公司 2020-08-11 CN disclosed
US-10688300-B2 Catheter systems ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) 2020-06-23 US disclosed
US-9289606-B2 System for electroporation therapy ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) 2016-03-22 US disclosed
EP-2425871-B1 Catheter systems ST JUDE MEDICAL ATRIAL FIBRILL (US) 2015-09-02 EP disclosed
US-20120059255-A1 CATHETER SYSTEMS ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. 2012-03-08 US disclosed
EP-2425871-A2 Catheter systems St. Jude Medical, Atrial Fibrillation Division, Inc. (US) 2012-03-07 EP disclosed
US-8129532-B2 Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use THE UNIVERSITY OF CONNECTICUT (US) 2012-03-06 US disclosed
US-20090042227-A1 AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2009-02-12 US disclosed
EP-1026222-B1 Organic material for electroluminescent device and electroluminescent device using the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2002-09-18 EP disclosed
US-6391482-B1 4,4,8,8-TETRAKIS(1H-PYRAZOL-1-YL)PYRAZABOLE; HIGH SPEED RESPONSE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-05-21 US disclosed
EP-1026222-A2 Organic material for electroluminescent device and electroluminescent device using the same Matsushita Electric Industrial Co., Ltd. (JP) 2000-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042227-A1 AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE NLN, NME4, OAT BACE1 4401/4885ALDH1A1 4559/4885CYP2A6 4007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.