Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074573 | 1.00 | MAPT (0.66) | MAPTNR1I2PGRADORA3PTGS2 | |
| SCHEMBL29980649 | 0.90 | MAPT (0.58) | MAPTNR1I2PGRADORA3PTGS2 | |
| SCHEMBL25624428 | 0.89 | MAPT (0.62) | MAPTNR1I2PGRADORA3PTGS2 | |
| SCHEMBL11101562 | 0.89 | MAPT (0.59) | MAPTNR1I2PGRADORA3PTGS2 | |
| SCHEMBL19284481 | 0.89 | MAPT (0.59) | MAPTNR1I2PGRADORA3PTGS2 | |
| SCHEMBL5168966 | 0.89 | ALDH1A1 (0.59) | MAPTNR1I2PGRADORA3PTGS2 | |
| SCHEMBL5168959 | 0.89 | ALDH1A1 (0.59) | MAPTNR1I2PGRADORA3PTGS2 | |
| SCHEMBL11330152 | 0.86 | NR1I2 (0.79) | MAPTNR1I2PGRADORA3PTGS2 | |
| SCHEMBL11330132 | 0.86 | NR1I2 (0.79) | MAPTNR1I2PGRADORA3PTGS2 | |
| SCHEMBL22100454 | 0.86 | MAPT (0.85) | MAPTNR1I2PGRADORA3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101092372-B | Method for practical synthesizing optically active alpha amino pimelic acid ester or monoester | YAOMINGKANGDE NEW MEDICINES DEV CO LTD SHANGHAI | 2011-09-21 | — | — | CN | disclosed |
| US-7435861-B2 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | CARDAX PHARMACEUTICALS, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| CN-101092372-A | Method for practical synthesizing optically active alpha amino pimelic acid ester or monoester | YAOMINGKANGDE NEW MEDICINES DE (CN) | 2007-12-26 | — | — | CN | disclosed |
| US-20060293545-A1 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | CARDAX PHARMA, INC. | 2006-12-28 | — | — | US | disclosed |
| US-20060183185-A1 | Method for the synthesis of astaxanthin | CARDAX PHARMACEUTICALS, INC. | 2006-08-17 | — | — | US | disclosed |
| US-20060178538-A1 | Methods for the synthesis of chiral dihydroxy intermediates useful for the chiral synthesis of carotenoids | CARDAX PHARMACEUTICALS, INC. | 2006-08-10 | — | — | US | disclosed |
| US-20060167319-A1 | Methods for the synthesis of unsaturated ketone intermediates useful for the synthesis of carotenoids | CARDAX PHARMACEUTICALS, INC. | 2006-07-27 | — | — | US | disclosed |
| US-20060088905-A1 | Methods for the synthesis of zeazanthin | CARDAX PHARMACEUTICALS, INC. | 2006-04-27 | — | — | US | disclosed |
| US-20060088904-A1 | Methods for the synthesis of astaxanthin | CARDAX PHARMACEUTICALS, INC. | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060088904-A1 | Methods for the synthesis of astaxanthin | HSD17B7, CYP51A1, HSD11B1 | MAPT 4401/4885NR1I2 1845/4885PGR 3398/4885 |
| US-20060293545-A1 | carotenes or xanthophylls, used as free radical scavengers; cytoprotective agents; oxidation resistance | TXNRD2, TXN2, TXNRD1 | MAPT 4552/4885NR1I2 968/4885PGR 2575/4885 |
| US-20060178538-A1 | Methods for the synthesis of chiral dihydroxy intermediates useful for the chiral synthesis of carotenoids | HSD17B7, DHPS, DHCR7 | MAPT 4658/4885NR1I2 1671/4885PGR 2015/4885 |
| US-20060167319-A1 | Methods for the synthesis of unsaturated ketone intermediates useful for the synthesis of carotenoids | DHPS, HSD17B7, COASY | MAPT 4097/4885NR1I2 2270/4885PGR 2014/4885 |
| US-20060088905-A1 | Methods for the synthesis of zeazanthin | DHPS, CYP51A1, HSD17B7 | MAPT 3380/4885NR1I2 2078/4885PGR 3438/4885 |
| US-20060183185-A1 | Method for the synthesis of astaxanthin | SQLE, HSD17B7, CYP51A1 | MAPT 4514/4885NR1I2 1576/4885PGR 3208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.