Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | GNG2 | P59768 | 2/20 | 0.36 |
| ▸ | GNB1 | P62873 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730699 | 0.73 | MEN1 (0.57) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL18527386 | 0.72 | EGFR (0.51) | MEN1KMT2APOLBHPGDKDM4E | |
| SCHEMBL21316776 | 0.67 | NQO1 (0.56) | MEN1KMT2AUSP2POLBAPP | |
| SCHEMBL2775968 | 0.63 | USP2 (0.63) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL1752327 | 0.62 | GABRP (0.49) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL6803555 | 0.61 | CYP3A4 (0.73) | MEN1KMT2AHPGDKDM4ECYP3A4 | |
| SCHEMBL21151072 | 0.61 | KMT2A (0.60) | MEN1KMT2AUSP2POLBATM | |
| SCHEMBL29574854 | 0.59 | MEN1 (0.42) | MEN1KMT2AUSP2POLBALPL | |
| SCHEMBL5941127 | 0.56 | HPGD (0.56) | MEN1KMT2APOLBATML3MBTL1 | |
| SCHEMBL28548212 | 0.56 | MAOA (0.35) | MEN1KMT2AUSP2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885371-A1 | THERAPEUTIC COMPOSITIONS AND METHODS | The Texas A & M University System (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006124324-A1 | THERAPEUTIC COMPOSITIONS AND METHODS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2006-11-23 | — | — | WO | disclosed |