Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197077 | 0.82 | ELANE (0.50) | CYP3A4ACACBPPARAPPARGELANE | |
| SCHEMBL26417575 | 0.82 | ALDH1A1 (0.40) | KDM4EACACBEPHX2NR1H4PPARA | |
| SCHEMBL178527 | 0.82 | EPHX2 (0.51) | LOXL2MAPTEPHX2NR1H4PPARA | |
| SCHEMBL8008090 | 0.82 | LOXL2 (0.44) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| Hydrochloric Acid SCHEMBL3397561 | 0.80 | EPHX2 (0.50) | KDM4ECYP3A4MAPTEPHX2NR1H4 | |
| SCHEMBL2909428 | 0.80 | TAAR1 (0.52) | KDM4EMAPTPPARAPPARGALDH1A1 | |
| SCHEMBL2090694 | 0.77 | KIF11 (0.49) | MAPTEPHX2NR1H4PPARAALDH1A1 | |
| SCHEMBL11922720 | 0.77 | CHRM2 (0.46) | KDM4ECHRM2 | |
| SCHEMBL14805913 | 0.77 | PRMT6 (0.45) | KDM4ECYP3A4MAPTNOS3NOS1 | |
| SCHEMBL26746 | 0.76 | SLC6A2 (0.44) | KDM4ECYP3A4MAPTACACBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580780-B2 | 6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist | ELI LILLY AND COMPANY (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120028961-A1 | 6 Substituted 2, 3,4,5 Tetrahydro-1H-Benzo[d]Azepines as 5-HT2c Receptor Agonist | ELI LILLY AND COMPANY (US) | 2012-02-02 | — | — | US | disclosed |
| EP-0064702-B1 | 4-TERT.-BUTOXYBENZYL AMINES | BASF Aktiengesellschaft (DE) | 1984-05-02 | — | — | EP | disclosed |
| EP-0064702-A1 | 4-Tert.-butoxybenzyl amines | BASF Aktiengesellschaft (DE) | 1982-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028961-A1 | 6 Substituted 2, 3,4,5 Tetrahydro-1H-Benzo[d]Azepines as 5-HT2c Receptor Agonist | HTR2C, HTR4, HTR1A | LOXL2 2235/4885KDM4E 623/4885CYP3A4 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.