Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547235 | 0.91 | ALDH1A1 (0.48) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL20610397 | 0.88 | ALDH1A1 (0.40) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL8909554 | 0.87 | ALDH1A1 (0.52) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL27788160 | 0.85 | ALDH1A1 (0.38) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL14759196 | 0.81 | NAAA (0.50) | ALDH1A1ATMHCAR2TSHRNAAA | |
| SCHEMBL11260401 | 0.80 | ALDH1A1 (0.39) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL7383760 | 0.80 | TSHR (0.46) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL8084070 | 0.80 | ALDH1A1 (0.45) | ALDH1A1ATMHCAR2TSHRHPGD | |
| SCHEMBL6661517 | 0.80 | CA12 (0.42) | ALDH1A1HPGDCA12CA9AKR1B1 | |
| SCHEMBL25226358 | 0.79 | NAAA (0.53) | ALDH1A1HCAR2TSHRNAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288606-B2 | Magnesium, titanium, and halogen; internal electron donor, ethyl N-Boc-sarcosine, ethyl N-propionyl sarcosine, ethyl N-Boc-pipercolinate, N-carbobenzyloxy-L-proline methyl ester; polymerize propylene and ethylene or alpha-olefin; internal modifier which does not contain a phthalate derivative | INEOS USA LLC (US) | 2012-10-16 | — | — | US | claimed |
| EP-1866347-B1 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INEOS TECH USA LLC (US) | 2018-05-09 | — | — | EP | disclosed |
| US-8288606-B2 | Magnesium, titanium, and halogen; internal electron donor, ethyl N-Boc-sarcosine, ethyl N-propionyl sarcosine, ethyl N-Boc-pipercolinate, N-carbobenzyloxy-L-proline methyl ester; polymerize propylene and ethylene or alpha-olefin; internal modifier which does not contain a phthalate derivative | INEOS USA LLC (US) | 2012-10-16 | — | — | US | disclosed |
| US-20080125614-A1 | Propylene polymer catalyst donor component | INNOVENE USA (US) | 2008-05-29 | — | — | US | disclosed |
| EP-1866347-A2 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INEOS USA LLC (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006110234-A2 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INEOS USA LLC (US) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125614-A1 | Propylene polymer catalyst donor component | RAD52, PGR, DRD2 | ALDH1A1 4619/4885ATM 1439/4885HCAR2 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.