SCHEMBL5077779

SCHEMBL5077779

C[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MME P08473 5/20 0.40
LTA4H P09960 3/20 0.40
ANPEP P15144 2/20 0.38
ACE P12821 1/20 0.38
ECE1 P42892 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22503730 1.00 MME (0.40) MMELTA4HANPEPACEECE1
SCHEMBL5077777 1.00 MME (0.40) MMELTA4HANPEPACEECE1
Hydrochloric Acid SCHEMBL21724484 0.99 MME (0.39) MMELTA4HANPEPACEECE1
Hydrochloric Acid SCHEMBL21724486 0.99 MME (0.39) MMELTA4HANPEPACEECE1
SCHEMBL34470404 0.94 MME (0.36) MMELTA4HANPEP
SCHEMBL29590996 0.92 OPRD1 (0.36) MMELTA4HANPEP
SCHEMBL29794242 0.92 MME (0.36) MMELTA4HANPEPACEECE1
SCHEMBL29630414 0.92 OPRD1 (0.36) MMELTA4HANPEP
SCHEMBL30799829 0.89 GHSR (0.37)
SCHEMBL10057501 0.89 OPRD1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295762-A1 COMPOSITE BIOACTIVE COMPOSITIONS AND APPLICATIONS THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-09-25 US claimed
WO-2025128968-A1 AZA GLP-1-BASED THERAPEUTIC ANALOGUES THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-06-19 WO claimed
WO-2025123045-A1 PREDICTIVE AND DIAGNOSTIC SCREENING METHODS FOR ENDOMETRIAL CANCER ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-06-12 WO claimed
US-20250108031-A1 FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO BACH BIOSCIENCES, LLC 2025-04-03 US claimed
EP-3505533-B1 SYNTHESIS METHOD FOR LOW-RACEMIZATION IMPURITY LIRAGLUTIDE SHENZHEN JYMED TECH CO LTD (CN) 2025-01-15 EP claimed
US-12053450-B2 FAP-activated therapeutic agents, and uses related thereto BACH BIOSCIENCES, LLC (US) 2024-08-06 US claimed
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 US claimed
US-12023316-B2 FAP-activated therapeutic agents, and uses related thereto BACH BIOSCIENCES, LLC (US) 2024-07-02 US claimed
EP-4299134-A2 FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO Bach Biosciences, LLC (US) 2024-01-03 EP claimed
US-20230390409-A1 FAP-ACTIVATED SERUM EXTENDED HALF-LIFE THERAPEUTIC CONJUGATES AVACTA LIFE SCIENCES LIMITED (GB) 2023-12-07 US claimed
CN-113967258-A FAP-activated therapeutics and uses related thereto 塔夫茨大学信托人 2022-01-25 CN claimed
CN-113956325-A FAP-activated therapeutics and uses related thereto 塔夫茨大学信托人 2022-01-21 CN claimed
US-20210088539-A1 AUTOMATED SAMPLE QUALITY ASSESSMENT METABOLON, INC. 2021-03-25 US claimed
US-10890592-B2 Automated sample quality assessment METABOLON, INC. (US) 2021-01-12 US claimed
EP-0291626-A2 Process for the preparation of optically-active cyanomethyl esters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-23 EP claimed
US-4570017-A Preparation of optically-active (mixed) anhydrides and acids SHELL OIL COMPANY (US) 1986-02-11 US claimed
US-4560515-A NON-SYMMETRICAL KETENE REACTED WITH A-HYDROXYNITRILE; TERTUARY AMINE CATALYST SHELL OIL COMPANY (US) 1985-12-24 US claimed
US-4529810-A Preparation of optically-active alpha-substituted carboxylic esters and acids SHELL OIL COMPANY (US) 1985-07-16 US claimed
EP-0116914-A1 Preparation of optically-active alpha-substituted carboxylic esters and acids E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-08-29 EP claimed
EP-0109681-A2 process for the preparation of optically-active cyanomethyl esters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295762-A1 COMPOSITE BIOACTIVE COMPOSITIONS AND APPLICATIONS THEREOF BMP2, BMP1, MATR3 MME 3208/4885LTA4H 1858/4885ANPEP 2730/4885
US-20250108031-A1 FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO FAP, FIBP, GOT1 MME 1245/4885LTA4H 963/4885ANPEP 93/4885
US-20230390409-A1 FAP-ACTIVATED SERUM EXTENDED HALF-LIFE THERAPEUTIC CONJUGATES FAP, FIBP, FUCA2 MME 247/4885LTA4H 1296/4885ANPEP 32/4885
US-12023316-B2 FAP-activated therapeutic agents, and uses related thereto FAP, FIBP, GOT1 MME 1245/4885LTA4H 963/4885ANPEP 93/4885
US-12053450-B2 FAP-activated therapeutic agents, and uses related thereto FAP, FIBP, GOT1 MME 1245/4885LTA4H 963/4885ANPEP 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.