Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182778 | 0.84 | ALDH1A1 (0.42) | THRBTSHRKMT2AALDH1A1MAPK1 | |
| SCHEMBL27778550 | 0.80 | HTR6 (0.42) | THRBTHRATSHRALDH1A1GAA | |
| SCHEMBL30055648 | 0.76 | THRB (0.50) | THRBKMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL1371361 | 0.74 | THRB (0.47) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL28546201 | 0.73 | THRB (0.43) | THRBTHRATSHRKMT2AALDH1A1 | |
| SCHEMBL5412466 | 0.73 | ALDH1A1 (0.47) | CTSBKMT2ATAAR1ALDH1A1LMNA | |
| SCHEMBL27809282 | 0.72 | TSHR (0.63) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL28326939 | 0.72 | THRB (0.42) | THRBTHRATSHRKMT2AALDH1A1 | |
| SCHEMBL10179924 | 0.71 | CTSB (0.53) | CTSBKMT2ATAAR1POLBHSD11B1 | |
| SCHEMBL28767937 | 0.71 | THRB (0.51) | THRBTHRATSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541550-B1 | ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER | OTSUKA CHEMICAL CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |