Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.54 |
| ▸ | GABRD | O14764 | 2/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.54 |
| ▸ | GABRE | P78334 | 2/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.54 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14360718 | 0.86 | GABRP (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15722835 | 0.85 | LMNA (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15871660 | 0.84 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15722833 | 0.81 | FFAR4 (0.57) | LMNA | |
| SCHEMBL15722858 | 0.81 | FFAR4 (0.57) | LMNA | |
| SCHEMBL9968625 | 0.81 | FFAR4 (0.57) | LMNA | |
| SCHEMBL7794193 | 0.81 | FFAR4 (0.57) | LMNA | |
| SCHEMBL244922 | 0.81 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL760414 | 0.81 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17956711 | 0.80 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60072816-A | — | — | None | — | — | JP | disclosed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| EP-3661901-B1 | SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS | EASTMAN CHEM CO (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3416729-B1 | PRO-FRAGRANCE COMPOSITION | AQDOT LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-108601958-B | Pro-fragrance compositions | 爱客多有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| US-7414155-B2 | Process for the hydroformylation of an ethylenically unsaturated compound | SHELL OIL COMPANY (US) | 2008-08-19 | — | — | US | disclosed |
| US-20070297993-A1 | Novel Use of Nonenolide | SYMRISE GMBH & CO. KG (DE) | 2007-12-27 | — | — | US | disclosed |
| EP-1542798-B1 | PROCESS FOR THE HYDROFORMYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND USING A BIDENTATE DIPHOSPHINE COMPOSITION WITH A BRIDGING GROUP COMPRISING SP2 HYBRIDIZED CARBON ATOMS BOUND TO THE PHOSPHOROUS ATOMS | SHELL INT RESEARCH (NL) | 2007-11-14 | — | — | EP | disclosed |
| US-20070238892-A1 | PROCESS FOR THE HYDROFORMYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND | DRENT EIT | 2007-10-11 | — | — | US | disclosed |
| US-7250538-B2 | Process for the hydroformylation of an ethylenically unsaturated compound | SHELL OIL COMPANY (US) | 2007-07-31 | — | — | US | disclosed |
| EP-1542798-A2 | PROCESS FOR THE HYDROFORMYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND USING A BIDENTATE DIPHOSPHINE COMPOSITION WITH A BRIDGING GROUP COMPRISING SP2 HYBRIDIZED CARBON ATOMS BOUND TO THE PHOSPHOROUS ATOMS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2005-06-22 | — | — | EP | disclosed |
| US-20040167362-A1 | Process for the hydroformylation of an ethylenically unsaturated compound | SHELL OIL COMPANY | 2004-08-26 | — | — | US | disclosed |
| WO-2004028689-A2 | PROCESS FOR THE HYDROFORMYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND USING A BIDENTATE DIPHOSPHINE COMPOSITION WITH A BRIDGING GROUP COMPRISING SP2 HYBRIDIZED CARBON ATOMS BOUND TO THE PHOSPHOROUS ATOMS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2004-04-08 | — | — | WO | disclosed |
| JP-S6072816-A | SLEEP ADJUSTING AND PSYCHONEUROTIC AGENT | MOCHIDA PHARMACEUT CO LTD | 1985-04-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | GABRP 623/4885GABRD 1623/4885GABRA1 1819/4885 |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | GABRP 199/4885GABRD 897/4885GABRA1 349/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | GABRP 623/4885GABRD 1623/4885GABRA1 1819/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | GABRP 623/4885GABRD 1623/4885GABRA1 1819/4885 |
| US-20070297993-A1 | Novel Use of Nonenolide | TAS2R14, TAS2R4, TAS2R7 | GABRP 2395/4885GABRD 2143/4885GABRA1 2376/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | GABRP 623/4885GABRD 1623/4885GABRA1 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.