SCHEMBL5085401

SCHEMBL5085401

CC(C)(CO[Si](C)(C)Cc1ccccc1)CO[Si](C)(C)Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.36
SLC6A2 P23975 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
TSHR P16473 3/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
CYP2D6 P10635 1/20 0.34
TP53 P04637 1/20 0.33
AOC3 Q16853 1/20 0.32
SQLE Q14534 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
AKT1 P31749 1/20 0.32
RECQL P46063 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078173 0.93 NUDT1 (0.33) TAAR1SLC6A2NR1H2NR1H3TSHR
SCHEMBL5075172 0.90 ALDH1A1 (0.38) TAAR1SLC6A2NR1H2NR1H3TSHR
SCHEMBL5075216 0.87 MAPT (0.32) NR1H2NR1H3ALDH1A1SQLE
SCHEMBL5081767 0.81 TAAR1 (0.38) TAAR1SLC6A2NR1H2NR1H3TSHR
SCHEMBL5085393 0.81 TDP1 (0.38) TAAR1SLC6A2TSHRALDH1A1LMNA
SCHEMBL109170 0.78 TP53 (0.42) TAAR1SLC6A2NR1H2NR1H3TSHR
SCHEMBL5081838 0.78 SIGMAR1 (0.33) TAAR1SLC6A2NR1H2NR1H3TSHR
SCHEMBL5077166 0.76 LMNA (0.35) TAAR1TSHRALDH1A1LMNATP53
SCHEMBL5078348 0.76 SLC6A2 (0.34) TAAR1SLC6A2NR1H2NR1H3LMNA
SCHEMBL5388447 0.74 TSHR (0.42) TAAR1NR1H2NR1H3TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed