SCHEMBL50825

SCHEMBL50825

CCCC(Oc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1)Oc1ccc(S(=O)(=O)c2ccc(OC/C=C/COc3ccc(S(=O)(=O)c4ccc(O)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
PKM P14618 2/20 0.46
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
LMNA P02545 1/20 0.45
KMT2A Q03164 1/20 0.45
CTRC Q99895 1/20 0.43
ELANE P08246 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
LTA4H P09960 4/20 0.36
NR5A1 Q13285 1/20 0.36
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
RECQL P46063 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51737 0.90 GAA (0.48) GAAPKMALDH1A1L3MBTL1LMNA
SCHEMBL51431 0.89 PKM (0.56) GAAPKMALDH1A1L3MBTL1LMNA
SCHEMBL10192348 0.88 CTRC (0.40) GAAPKMALDH1A1L3MBTL1LMNA
SCHEMBL1396022 0.85 PKM (0.51) GAAPKMALDH1A1L3MBTL1LMNA
SCHEMBL51006 0.85 PKM (0.51) GAAPKMALDH1A1L3MBTL1LMNA
SCHEMBL50900 0.84 PKM (0.58) GAAPKMALDH1A1LMNAELANE
SCHEMBL51114 0.84 PKM (0.58) GAAPKMALDH1A1LMNAELANE
SCHEMBL50901 0.84 PKM (0.58) GAAPKMALDH1A1LMNAELANE
SCHEMBL51566 0.84 PKM (0.58) GAAPKMALDH1A1LMNAELANE
SCHEMBL51420 0.84 PKM (0.58) GAAPKMALDH1A1LMNAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190152248-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE RICOH COMPANY, LTD. (JP) 2019-05-23 US disclosed
EP-3475095-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE Ricoh Company, Ltd. (JP) 2019-05-01 EP disclosed
EP-2484534-B1 RECORDING MATERIAL USING PHENOLIC COMPOUND NIPPON SODA CO (JP) 2019-01-16 EP disclosed
EP-1930318-B1 Process for producing diphenyl sulfone compound NIPPON SODA CO (JP) 2017-03-08 EP disclosed
EP-2289704-B1 COLOR-DEVELOPING COMPOSITION AND RECORDING MATERIAL CONTAINING THE SAME NIPPON SODA CO (JP) 2014-05-14 EP disclosed
US-8551911-B2 Recording material using phenolic compound NIPPON SODA CO., LTD. (JP) 2013-10-08 US disclosed
US-8546299-B2 Color-developing composition and recording material containing the same NIPPON SODA CO., LTD. (JP) 2013-10-01 US disclosed
EP-1273570-B1 PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND NIPPON SODA CO (JP) 2013-07-17 EP disclosed
EP-2484534-A1 RECORDING MATERIAL USING PHENOLIC COMPOUND Nippon Soda Co., Ltd. (JP) 2012-08-08 EP disclosed
US-20120186490-A1 RECORDING MATERIAL USING PHENOLIC COMPOUND NIPPON SODA CO., LTD. 2012-07-26 US disclosed
EP-2289704-A1 COLOR-DEVELOPING COMPOSITION AND RECORDING MATERIAL CONTAINING THE SAME Nippon Soda Co., Ltd. (JP) 2011-03-02 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
US-7619120-B2 Processes for the preparation of diphenylsulfone compounds NIPPON SODA CO., LTD. (JP) 2009-11-17 US disclosed
EP-1930318-A2 Process for producing diphenyl sulfone compound Nippon Soda Co., Ltd. (JP) 2008-06-11 EP disclosed
US-20050065377-A1 Processes for the preparation of diphenylsulfone compounds NIPPON SODA CO., LTD 2005-03-24 US disclosed
US-6831201-B2 Aqueous solution containing dihydroxydiphenyl sulfone monoether compound is adjusted pH to a preset value, extracted with an organic solvent and separated to an organic and an aqueous layers, and that water or water adjusted to a fixed pH NIPPON SODA CO., LTD. (JP) 2004-12-14 US disclosed
US-20030092941-A1 Process for producing diphenyl sulfone compound NIPPON SODA CO., LTD. (JP) 2003-05-15 US disclosed
EP-1273570-A1 PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND NIPPON SODA CO., LTD. (JP) 2003-01-08 EP disclosed
EP-0860429-B1 DIPHENYL SULFONE CROSSLINKING TYPE COMPOUNDS AND RECORDING MATERIALS USING THEM NIPPON SODA CO (JP) 2001-12-12 EP disclosed
US-6037308-A HIGH RECORDED IMAGE PRESERVABILITY NIPPON SODA CO., LTD. (JP) 2000-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190152248-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE CACNA1S, NCS1, TRPA1 GAA 3682/4885PKM 1477/4885ALDH1A1 257/4885
US-20030092941-A1 Process for producing diphenyl sulfone compound ASH2L, AP2S1, HACL2 GAA 1958/4885PKM 3024/4885ALDH1A1 943/4885
US-20050065377-A1 Processes for the preparation of diphenylsulfone compounds AP2S1, ASH2L, SRMS GAA 2093/4885PKM 2382/4885ALDH1A1 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.