Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509060 | 0.87 | CYP1A1 (0.56) | CYP3A4MAPTTP53CYP19A1XDH | |
| SCHEMBL2319151 | 0.85 | CYP19A1 (0.57) | PTGS1MAPK14CYP3A4MAPTTP53 | |
| SCHEMBL28616927 | 0.83 | RECQL (0.44) | PTGS1CYP3A4MAPTCYP19A1CYP1A1 | |
| SCHEMBL7200862 | 0.81 | CYP1A1 (0.54) | PTGS1MAPK14CYP3A4MAPTTP53 | |
| SCHEMBL15544306 | 0.80 | RECQL (0.56) | PTGS1MAPK14CYP3A4MAPTHPGD | |
| SCHEMBL28464161 | 0.80 | CYP1A1 (0.53) | CYP3A4MAPTTP53CYP19A1XDH | |
| SCHEMBL8063267 | 0.78 | GSK3B (0.49) | CYP3A4MAPTTP53CYP19A1XDH | |
| SCHEMBL3487578 | 0.78 | CYP3A4 (0.52) | PTGS1CYP3A4MAPTTP53CYP19A1 | |
| SCHEMBL349722 | 0.78 | CYP3A4 (0.52) | PTGS1CYP3A4MAPTTP53CYP19A1 | |
| SCHEMBL773768 | 0.78 | CYP19A1 (0.47) | CYP3A4MAPTTP53CYP19A1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890378-A | FOXO1 activity-inhibiting composition | 三得利控股株式会社 | 2019-06-14 | — | — | CN | disclosed |
| US-20170071902-A1 | NOX INHIBITOR AND NFkB INHIBITOR CONTAINING METHOXYFLAVONE | SUNTORY HOLDINGS LIMITED (JP) | 2017-03-16 | — | — | US | disclosed |
| WO-2007115181-A9 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEM CO (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| WO-2007115181-A2 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-10-11 | — | — | WO | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | PTGS1 2062/4885MAPK14 2483/4885CYP3A4 17/4885 |
| US-20170071902-A1 | NOX INHIBITOR AND NFkB INHIBITOR CONTAINING METHOXYFLAVONE | NOX1, NFKBIA, NOX5 | PTGS1 157/4885MAPK14 155/4885CYP3A4 1665/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | PTGS1 92/4885MAPK14 1024/4885CYP3A4 3010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.