Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560133 | 0.78 | ATM (0.58) | TAAR1ATMSIGMAR1NPC1RAB9A | |
| SCHEMBL11097946 | 0.76 | SIGMAR1 (0.42) | TAAR1ATMSIGMAR1CYP3A4L3MBTL1 | |
| SCHEMBL26964152 | 0.72 | ATM (0.50) | TAAR1ATMSIGMAR1NPC1RAB9A | |
| SCHEMBL28453487 | 0.71 | TP53 (0.46) | TAAR1ATMSIGMAR1ALDH1A1LMNA | |
| SCHEMBL1406143 | 0.71 | SIGMAR1 (0.64) | TAAR1ATMSIGMAR1NPC1RAB9A | |
| SCHEMBL9768698 | 0.71 | SIGMAR1 (0.58) | TAAR1ATMSIGMAR1NPC1RAB9A | |
| SCHEMBL11103634 | 0.71 | SIGMAR1 (0.44) | TAAR1ATMSIGMAR1NPC1RAB9A | |
| SCHEMBL16415958 | 0.70 | NPC1 (0.58) | TAAR1ATMSIGMAR1NPC1RAB9A | |
| SCHEMBL1878 | 0.70 | TAAR1 (1.00) | TAAR1ATMSIGMAR1NPC1RAB9A | |
| SCHEMBL19355275 | 0.70 | TAAR1 (1.00) | TAAR1ATMSIGMAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624851-B1 | HAIR CARE APPLICATIONS OF EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES WITH NITROGEN ATOMS | DOW CORNING (US) | 2014-05-28 | — | — | EP | disclosed |
| US-7902293-B2 | Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups | DOW CORNING CORPORATION (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1625132-B1 | METHOD OF PREPARING EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES HAVING QUATERNARY AMMONIUM GROUPS | DOW CORNING (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20060269506-A1 | Personal care applications of emulsions containing elastomeric silanes and siloxanes with nitrogen atoms | DOW CORNING CORPORATION (US) | 2006-11-30 | — | — | US | disclosed |
| US-20060193805-A1 | Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups | DOW SILICONES CORPORATION | 2006-08-31 | — | — | US | disclosed |
| EP-1426398-B1 | Method of making emulsion containing quaternary ammonium functional silanes and siloxanes | DOW CORNING (US) | 2006-07-05 | — | — | EP | disclosed |
| EP-1624851-A1 | PERSONAL CARE APPLICATIONS OF EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES WITH NITROGEN ATOMS | Dow Corning Corporation (US) | 2006-02-15 | — | — | EP | disclosed |
| EP-1625132-A1 | METHOD OF PREPARING EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES HAVING QUATERNARY AMMONIUM GROUPS | Dow Corning Corporation (US) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004103326-A1 | PERSONAL CARE APPLICATIONS OF EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES WITH NITROGEN ATOMS | DOW CORNING CORPORATION (US) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004104013-A1 | METHOD OF PREPARING EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES HAVING QUATERNARY AMMONIUM GROUPS | DOW CORNING CORPORATION (US) | 2004-12-02 | — | — | WO | disclosed |
| US-6787603-B2 | REACTING EPOXIDE OR HALOHYDRIN DERIVATIZED NITROGEN ONIUM COMPOUND WITH AN AMINO FUNCTIONALIZED POLYSILOXANE IN WATER CONTAINING SURFACTANT | DOW CORNING CORPORATION | 2004-09-07 | — | — | US | disclosed |
| EP-1426398-A1 | Method of making emulsion containing quaternary ammonium functional silanes and siloxanes | DOW CORNING CORPORATION (US) | 2004-06-09 | — | — | EP | disclosed |
| US-20040102570-A1 | METHOD OF MAKING EMULSION CONTAINING QUATERNARY AMMONIUM FUNCTIONAL SILANES AND SILOXANES | DOW SILICONES CORPORATION | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060193805-A1 | Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups | COPE, ITCH, CUTA | TAAR1 2944/4885ATM 2800/4885SIGMAR1 1471/4885 |
| US-20060269506-A1 | Personal care applications of emulsions containing elastomeric silanes and siloxanes with nitrogen atoms | CUTA, POLR1C, ITCH | TAAR1 2778/4885ATM 2906/4885SIGMAR1 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.