SCHEMBL5086308

SCHEMBL5086308

CC(=O)O[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 3/20 0.53
LGALS8 O00214 2/20 0.53
LGALS4 P56470 2/20 0.53
LGALS9 O00182 1/20 0.48
LGALS1 P09382 1/20 0.48
LGALS7; LGALS7B P47929 1/20 0.48
IGF2R P11717 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
AMY1A P0DUB6 1/20 0.47
TYR P14679 6/20 0.45
CD69 Q07108 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5544380 1.00 LGALS3 (0.53) LGALS3LGALS8LGALS4LGALS9LGALS1
SCHEMBL16715894 0.91 LGALS3 (0.45) LGALS3LGALS8LGALS4LGALS9LGALS1
SCHEMBL7521033 0.90 AMY1A (0.43) LGALS3LGALS8LGALS4LGALS9LGALS1
SCHEMBL229613 0.89 SLC28A3 (0.50) LGALS8TYRCD69
SCHEMBL22026379 0.89 SLC28A3 (0.50) LGALS8TYRCD69
SCHEMBL4703623 0.89 SLC28A3 (0.50) LGALS8TYRCD69
SCHEMBL19603336 0.89 SLC28A3 (0.50) LGALS8TYRCD69
SCHEMBL3144972 0.89 SLC28A3 (0.50) LGALS8TYRCD69
SCHEMBL22047951 0.89 SLC28A3 (0.50) LGALS8TYRCD69
SCHEMBL16285372 0.89 SLC28A3 (0.50) LGALS8TYRCD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104471071-B Sugar esters as inducers of gene expression 青岛蔚蓝生物集团有限公司 2021-05-28 CN disclosed
US-20210079438-A1 CARBOHYDRATE ESTERS AS INDUCERS FOR GENE EXPRESSION QINGDAO VLAND BIOTECH GROUP CO LTD (CN) 2021-03-18 US disclosed
US-10870873-B2 Method of using carbohydrate esters as inducers for gene expression QINGDAO VIAND BIOTECH GROUP CO., LTD. (CN) 2020-12-22 US disclosed
CN-107012188-B Preparation method of gene expression inducer 青岛蔚蓝生物集团有限公司 2020-10-30 CN disclosed
CN-106977558-B Method for producing sophorose ester compound 青岛蔚蓝生物集团有限公司 2020-06-09 CN disclosed
CN-107011391-B Method for producing sophorose 青岛蔚蓝生物集团有限公司 2020-05-22 CN disclosed
US-20180327804-A1 CARBOHYDRATE ESTERS AS INDUCERS FOR GENE EXPRESSION QINGDAO VLAND BIOTECH GROUP CO., LTD. (CN) 2018-11-15 US disclosed
US-10059973-B2 Carbohydrate esters as inducers for gene expression QINGDAO VLAND BIOTECH GROUP CO., LTD. (CN) 2018-08-28 US disclosed
US-20150152462-A1 Carbohydrate Esters as Inducers for Gene Expression SOPHORO BIOTECHNOLOGIES, LLC (US) 2015-06-04 US disclosed
CN-104666318-A Novel sulfated oligosaccharide derivatives PROGEN PHARMACEUTICALS LTD 2015-06-03 CN disclosed
EP-2875143-A1 CARBOHYDRATE ESTERS AS INDUCERS FOR GENE EXPRESSION Sophoro Biotechnologies LLC (US) 2015-05-27 EP disclosed
WO-2014015179-A1 CARBOHYDRATE ESTERS AS INDUCERS FOR GENE EXPRESSION SOPHORO BIOTECHNOLOGIES, LLC (US) 2014-01-23 WO disclosed
US-20080207532-A1 Use of Nordihydroguaiaretic Acid Derivatives in the Treatment of Drug Resistant Cancer, Viral and Microbial Infection JOHNS HOPKINS UNIVERSITY (US) 2008-08-28 US disclosed
EP-1848418-A2 USE OF NORDIHYDROGUAIARETIC ACID DERIVATIVES IN THE TREATMENT OF DRUG RESISTANT CANCER, VIRAL AND MICROBIAL INFECTION Johns Hopkins University (US) 2007-10-31 EP disclosed
WO-2006041902-A2 USE OF NORDIHYDROGUAIARETIC ACID DERIVATIVES IN THE TREATMENT OF DRUG RESISTANT CANCER, VIRAL AND MICROBIAL INFECTION JOHNS HOPKINS UNIVERSITY (US) 2006-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10870873-B2 Method of using carbohydrate esters as inducers for gene expression MGAM, HSD17B14, ERG28 LGALS3 818/4885LGALS8 689/4885LGALS4 454/4885
US-20180327804-A1 CARBOHYDRATE ESTERS AS INDUCERS FOR GENE EXPRESSION HSD17B14, MGAM, ATF4 LGALS3 738/4885LGALS8 583/4885LGALS4 382/4885
US-20080207532-A1 Use of Nordihydroguaiaretic Acid Derivatives in the Treatment of Drug Resistant Cancer, Viral and Microbial Infection ABCC1, ABCB1, HPGD LGALS3 2065/4885LGALS8 2947/4885LGALS4 2715/4885
US-10059973-B2 Carbohydrate esters as inducers for gene expression HSD17B14, MGAM, ATF4 LGALS3 738/4885LGALS8 583/4885LGALS4 382/4885
US-20150152462-A1 Carbohydrate Esters as Inducers for Gene Expression HSD17B14, MGAM, ATF4 LGALS3 738/4885LGALS8 583/4885LGALS4 382/4885
US-20210079438-A1 CARBOHYDRATE ESTERS AS INDUCERS FOR GENE EXPRESSION HSD17B14, MGAM, ATF4 LGALS3 738/4885LGALS8 583/4885LGALS4 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.