SCHEMBL5087631

SCHEMBL5087631

C=CC(=O)OC(CSc1ccc(Br)cc1)CSc1ccc(Br)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.42
MAOA P21397 1/20 0.42
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
TGM2 P21980 2/20 0.36
CYP2C19 P33261 1/20 0.36
HSP90AA1 P07900 1/20 0.36
KCNH2 Q12809 1/20 0.36
LMNA P02545 2/20 0.36
F13A1 P00488 1/20 0.36
TGM1 P22735 1/20 0.36
TGM3 Q08188 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4758985 0.88 PPARD (0.39) SMN1; SMN2MAOAKMT2AMEN1ALDH1A1
SCHEMBL23722519 0.85 ALDH1A1 (0.39) SMN1; SMN2KMT2AMEN1LMNAALDH1A1
SCHEMBL5092611 0.85 HPGD (0.42) SMN1; SMN2KMT2AMEN1TGM2ALDH1A1
SCHEMBL5092633 0.84 MTNR1A (0.43) MAOAALDH1A1NPC1RAB9APPARG
SCHEMBL29734622 0.83 MAOA (0.48) MAOATGM2CA1CA2CA4
SCHEMBL5088929 0.83 MAOA (0.48) MAOATGM2CA1CA2CA4
SCHEMBL29734626 0.83 MAOA (0.48) MAOATGM2CA1CA2CA4
SCHEMBL30444663 0.82 SMN1; SMN2 (0.38) SMN1; SMN2MAOAKMT2AMEN1LMNA
SCHEMBL23391665 0.79 SMN1; SMN2 (0.43) SMN1; SMN2KMT2AMEN1TGM2HSP90AA1
SCHEMBL23722516 0.78 ANPEP (0.44) SMN1; SMN2KMT2AMEN1CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US claimed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US claimed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP claimed
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US disclosed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US disclosed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP disclosed
US-20080145545-A1 METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM CITIBANK, N.A., AS COLLATERAL AGENT 2008-06-19 US disclosed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US disclosed
EP-1512704-A1 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2005-03-09 EP disclosed
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY 2005-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom MACF1, WASF2, THEM6 SMN1; SMN2 3159/4885MAOA 3034/4885KMT2A 2677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.