SCHEMBL5092633

SCHEMBL5092633

C=CC(=O)OC(CSc1ccccc1)CSc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 4/20 0.43
MTNR1B P49286 4/20 0.43
FFAR1 O14842 1/20 0.42
THRB P10828 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
ALDH1A1 P00352 2/20 0.38
HCAR2 Q8TDS4 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
MMP2 P08253 3/20 0.35
MMP3 P08254 3/20 0.35
MMP9 P14780 3/20 0.35
MMP13 P45452 2/20 0.35
MAPK1 P28482 1/20 0.35
MMP1 P03956 1/20 0.35
MMP8 P22894 1/20 0.35
AKT1 P31749 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4759193 0.87 THRB (0.47) MTNR1AMTNR1BFFAR1THRBNPC1
SCHEMBL5092619 0.87 ALDH1A1 (0.42) MTNR1AMTNR1BFFAR1THRBALDH1A1
SCHEMBL5092611 0.84 HPGD (0.42) ALDH1A1NPC1RAB9AMAPK1
SCHEMBL23722519 0.84 ALDH1A1 (0.39) MTNR1AMTNR1BTHRBALDH1A1
SCHEMBL5087631 0.84 SMN1; SMN2 (0.42) MAOAALDH1A1NPC1RAB9APPARG
SCHEMBL5092612 0.84 MTNR1A (0.48) MTNR1AMTNR1BFFAR1THRBMAOA
SCHEMBL6752943 0.84 THRB (0.41) THRBALDH1A1MMP3
SCHEMBL6753001 0.84 MMP3 (0.47) MTNR1AMTNR1BTHRBNPC1MMP2
SCHEMBL23722516 0.84 ANPEP (0.44) ALDH1A1MAPK1
SCHEMBL5088929 0.83 MAOA (0.48) MTNR1AMTNR1BMAOAALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122063827-A Photoinitiation system and application thereof 甬江实验室 2026-05-19 CN claimed
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US claimed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US claimed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP claimed
US-20210246266-A1 HIGH DYNAMIC RANGE TWO-STAGE PHOTOPOLYMERS NATIONAL SCIENCE FOUNDATION 2021-08-12 US claimed
CN-122063827-A Photoinitiation system and application thereof 甬江实验室 2026-05-19 CN disclosed
CN-120865473-B Raw material composition for preparing modified acrylic optical material 江苏视科新材料股份有限公司 2026-02-10 CN disclosed
CN-120865483-B Raw material composition for preparing modified polyurethane optical material 江苏视科新材料股份有限公司 2026-01-27 CN disclosed
CN-121248453-A 1, 3-Bis (phenylthio) -2-propyl acrylate, preparation method thereof and application thereof as optical material modifier 江苏视科新材料股份有限公司 2026-01-02 CN disclosed
CN-121248453-A 1, 3-Bis (phenylthio) -2-propyl acrylate, preparation method thereof and application thereof as optical material modifier 江苏视科新材料股份有限公司 2026-01-02 CN disclosed
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US disclosed
CN-120865473-A Raw material composition for preparing modified acrylic optical material 江苏视科新材料股份有限公司 2025-10-31 CN disclosed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US disclosed
WO-2007062864-A2 POLYMER COMPOSITION HAVING A HIGH REFRACTIVE INDEX CORONIS GMBH (DE) 2007-06-07 WO disclosed
EP-1512704-A1 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2005-03-09 EP disclosed
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY 2005-03-03 US disclosed
EP-0064020-B1 SYNERGISTIC ANTIOXIDANT MIXTURES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-06-19 EP disclosed
US-4370434-A PHENOLS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-01-25 US disclosed
US-4362887-A ESTERS, THIO, POLYPROPYLENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-12-07 US disclosed
EP-0064020-A1 Synergistic antioxidant mixtures THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom MACF1, WASF2, THEM6 MTNR1A 2165/4885MTNR1B 3705/4885FFAR1 411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.