Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10072113 | 0.79 | BMPR1B (0.34) | KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL17723653 | 0.75 | — | — | |
| SCHEMBL10072451 | 0.73 | L3MBTL1 (0.38) | KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL29313307 | 0.71 | — | — | |
| SCHEMBL29892424 | 0.71 | TP53 (0.34) | KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2464256 | 0.67 | — | — | |
| SCHEMBL13660699 | 0.67 | — | — | |
| SCHEMBL958356 | 0.67 | — | — | |
| Bicarbonate SCHEMBL23649996 | 0.67 | L3MBTL1 (0.39) | KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL25261881 | 0.64 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612372-B2 | Oxopyridazinyl-phenyl-carbonohydrazonoyl dicyanide compound and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-04-28 | — | — | US | disclosed |
| US-20230278963-A1 | NOVEL OXOPYRIDAZINYL-PHENYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-09-07 | — | — | US | disclosed |
| EP-4169909-A1 | NOVEL OXOPYRIDAZINYL-PHENYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF | Korea Institute of Science and Technology (KR) | 2023-04-26 | — | — | EP | disclosed |
| CN-115867279-A | Novel oxopyridazinyl-phenyl-carbohydrazone acyldinitrile compounds and use thereof | 韩国科学技术研究院 | 2023-03-28 | — | — | CN | disclosed |
| US-7419979-B2 | Derivatives of 6-{4-[4-(1H-indole-2-sulphonyl)-piperazin-1-carbonyl-phenyl]}pyradizin-3-one | ASTRAZENECA AB (SE) | 2008-09-02 | — | — | US | disclosed |
| US-20070135441-A1 | New derivatives of 6-{4-[4-(1h-indole-2-sulphonyl)-piperazin-1-carbonyl-phenyl]}pyradizin-3-one | ASTRAZENECA AB (SE) | 2007-06-14 | — | — | US | disclosed |
| CN-1905883-A | Novel derivatives of 6- { 4- [ 4- (1H-indole-2-sulfonyl) -piperazine-1-carbonyl-phenyl ] } pyridazin-3-one | ASTRAZENECA AB (SE) | 2007-01-31 | — | — | CN | disclosed |
| EP-1706120-A1 | NEW DERIVATIVES OF 6- 4 4 - 1 H - INDOLE-2-SULPHONYL)-PIPERA ZIN-1-CARBONYL-PHENYL PYRADIZIN-3-ONE | AstraZeneca AB (SE) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005065688-A1 | NEW DERIVATIVES OF 6-4{4-[1H-INDOLE-2-SULPHONYL)-PIPERAZIN-1-CARBONYL-PHENYL]}PYRADIZIN-3-ONE | ASTRAZENECA AB (SE) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612372-B2 | Oxopyridazinyl-phenyl-carbonohydrazonoyl dicyanide compound and use thereof | MAPT, MAP2, MAP1B | KDM4E 1078/4885ALDH1A1 3523/4885SMN1; SMN2 87/4885 |
| US-20230278963-A1 | NOVEL OXOPYRIDAZINYL-PHENYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF | DPP4, QDPR, DPYD | KDM4E 2828/4885ALDH1A1 431/4885SMN1; SMN2 4686/4885 |
| US-20070135441-A1 | New derivatives of 6-{4-[4-(1h-indole-2-sulphonyl)-piperazin-1-carbonyl-phenyl]}pyradizin-3-one | HTR7, TRPC7, HRH4 | KDM4E 2216/4885ALDH1A1 1369/4885SMN1; SMN2 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.