SCHEMBL509008

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5225076	0.90	KCNH2 (0.51)	LMNAOXTRAVPR1AMEN1KMT2A
	SCHEMBL509432	0.89	BCHE (0.40)	LMNASCN8ASMN1; SMN2MAPT
	SCHEMBL508181	0.86	KCNH2 (0.47)	LMNAKCNH2SCN8AHSD17B10P2RX7
	SCHEMBL5229533	0.84	P2RX7 (0.50)	LMNAMEN1KMT2AP2RX7SMN1; SMN2
	SCHEMBL5228111	0.82	KCNH2 (0.53)	LMNAKCNH2HSD17B10P2RX7MAPT
	SCHEMBL508578	0.82	KCNH2 (0.53)	LMNAKCNH2SCN8ASMN1; SMN2
	SCHEMBL509451	0.81	CYP1A2 (0.45)	LMNAMEN1KMT2ASCN8AMAPT
	SCHEMBL5228148	0.81	KCNH2 (0.53)	LMNAKCNH2SCN8AHSD17B10P2RX7
	SCHEMBL5226919	0.79	KCNH2 (0.51)	LMNAKCNH2MAPT
	SCHEMBL5226456	0.79	KCNH2 (0.48)	KCNH2SCN8AP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.